Department of Pathology, Immunology and Laboratory Medicine http://pathology.ufl.edu College of Medicine Mon, 10 Jun 2013 17:41:59 +0000 en-US hourly 1 http://wordpress.org/?v=3.5.1 Welcome to the University of Florida Department of Pathology, Immunology and Laboratory Medicine! http://pathology.ufl.edu/2012/07/16/welcome-to-the-university-of-florida-department-of-pathology-immunology-and-laboratory-medicine/ http://pathology.ufl.edu/2012/07/16/welcome-to-the-university-of-florida-department-of-pathology-immunology-and-laboratory-medicine/#comments Mon, 16 Jul 2012 20:56:40 +0000 Angelo Biondini http://com-pathology.sites.medinfo.ufl.edu/?p=859 UF Department of Pathology, Immunology and Laboratory Medicine Chair Michael Clare-Salzler, M.D.

Department of Pathology, Immunology and Laboratory Medicine Chair Michael J. Clare-Salzler, M.D.

Welcome to the Department of Pathology, Immunology and Laboratory Medicine at the University of Florida College of Medicine. This website provides an overview of the Department, with links to information about our faculty, programs, core services, and our institution, as well as information about how to apply to our outstanding residency program or clinical fellowships.

The Department of Pathology is composed of six divisions, including:

Anatomic Pathology • Clinical Pathology
Experimental Pathology • Forensic Toxiclogy
UF PathLabs • Administration

With a rich tradition of excellence in clinical medicine, education and research, our faculty practices a multidisciplinary approach to pathology daily, while mentoring medical students at two area teaching hospitals and the area medical examiner’s office:

  • UF Health Shands Hospital: This 606-bed teaching hospital is the tertiary referral center for North Central Florida and South Georgia; it is also a major transplant center; a Trauma One center; and the only pediatric inpatient facility for North Central Florida.
  • Malcom Randall Veterans Affairs Medical Center: This 273-bed hospital is the central hub of the North Florida/South Georgia Veterans Affairs Health System and one of the busiest in medical facilities throughout the VA network.
  • Florida District 8 Medical Examiner’s Office: Because pathology is a critical tool for autopsies, some of the Department of Pathology’s pathologists serve a dual role at the District 8 Medical Examiner’s Office in Gainesville. When not performing official postmortem examinations for the state, our physicians put their skill to work at UF Autopsy Services.

As faculty physicians, we are united by our commitment to patient care, education and research. And it is our esteemed pleasure to welcome you to our Department.

Sincerely,

Michael J. Clare-Salzler, M.D.
Chair
Director, Center for Immunology and Transplantation
Stetson Professor of Experimental Pathology
Department of Pathology, Immunology and Laboratory Medicine
University of Florida College of Medicine

]]> http://pathology.ufl.edu/2012/07/16/welcome-to-the-university-of-florida-department-of-pathology-immunology-and-laboratory-medicine/feed/ 0 News http://pathology.ufl.edu/about/news/ http://pathology.ufl.edu/about/news/#comments Mon, 16 Jul 2012 20:55:09 +0000 Angelo Biondini http://com-pathology.sites.medinfo.ufl.edu/?p=3719 Learn all the latest news on our Department and faculty research here.

]]> http://pathology.ufl.edu/about/news/feed/ 0 Anatomic Pathology http://pathology.ufl.edu/2012/07/16/anatomic-pathology/ http://pathology.ufl.edu/2012/07/16/anatomic-pathology/#comments Mon, 16 Jul 2012 06:57:58 +0000 Angelo Biondini http://com-pathology.sites.medinfo.ufl.edu/?p=808 Anatomic pathology involves the diagnosis of disease by appraising tissue/organ specimens and whole bodies via gross, microscopic, chemical, immunologic and molecular examination techniques. The pathologists at the the Department of Pathology, Immunology and Laboratory Medicine practice and teach anatomic pathology daily within the University of Florida College of Medicine. Our Department focuses on the following anatomic pathology subspecialties:


 
]]> http://pathology.ufl.edu/2012/07/16/anatomic-pathology/feed/ 0 Clinical Pathology http://pathology.ufl.edu/2012/07/16/clinical-pathology/ http://pathology.ufl.edu/2012/07/16/clinical-pathology/#comments Mon, 16 Jul 2012 05:20:12 +0000 Angelo Biondini http://com-pathology.sites.medinfo.ufl.edu/?p=851 Clinical pathology helps physicians diagnose patient conditions and diseases by analyzing bodily fluids with instruments and equipment used in chemistry, hematology, microbiology and molecular pathology. The Department’s faculty physicians practice and teach clinical pathology at the University of Florida College of Medicine, providing services in the following clinical pathology subspecialties:

  • Chemistry: Our chemistry unit provides expert and timely advice in the selection and interpretation of laboratory tests used in the assessment of health and the diagnosis and management of disease.
  • Hematology
  • Immunology
  • Microbiology
  • Transfusion Services
  • Virology: The clinical virology laboratory at UF Health Shands Hospital performs viral culture and identification, rapid testing for influenza and respiratory syncytial virus, and specialized PCR testing for herpes simplex encephalitis, cytomegalovirus, BK virus and Epstein-Barr virus. Serologic diagnosis of EBV, HSV, CMV, toxoplasma and rubella, as well as autoimmune testing is also performed in this laboratory.
]]> http://pathology.ufl.edu/2012/07/16/clinical-pathology/feed/ 0 Experimental Pathology http://pathology.ufl.edu/2012/07/15/experimental-pathology/ http://pathology.ufl.edu/2012/07/15/experimental-pathology/#comments Sun, 15 Jul 2012 14:46:03 +0000 Angelo Biondini http://com-pathology.sites.medinfo.ufl.edu/?p=879

Experimental pathology involves the study of disease processes via the examination of cells, tissues or organs or bodily fluids from diseased organisms. The Department’s Experimental Pathology Division is composed of a diverse group of investigators who research the disease mechanisms. Their research covers five overlapping areas, including:

 

 

 

 

 

Cancer Research

The goal of the cancer group is to generate improved methods for cancer detection, diagnosis and treatment. Our faculty is capable of defining and screening drug candidates for their abilities to interact with target proteins, in addition to conducting preclinical testing using biochemical, biophysical, cellular and whole animal methods. Employing a strategy based on the atomic structures of proteins involved in specific mechanisms that promote uncontrolled cell growth and division, our interdisciplinary team pursues novel structure-based strategies to define therapeutic agents that can treat a diverse set of cancer cell types, including:
 

Breast • Pancreas • Liver • Colorectal • Lung • Multiple Myeloma • Lung • Prostate

Related Faculty Members
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Emerging Pathogens

Research interests include:

  • HIV pathogenesis
  • HCV pathogenesis and therapeutic approaches
  • Antibiotic resistance in enteric bacteria
  • Modeling of pathogen evolution Molecular docking approach to drug design
  • Vaccine design

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Immunology/Autoimmunity

The goal of our research is to understand the contribution of immune system to disease; to define mechanisms of disease; discover biomarkers; and develop effective treatments.

Our disease-related studies include basic and clinical research on all aspects of the immune system in:

  • Lupus;
  • Type-1 diabetes;
  • Viral infections; and
  • Cancer.

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Nephrolithiasis

This specialty focuses on investigating the fundamental mechanisms responsible for the formation of kidney stones to better manage and prevent kidney stone disease. As most kidney stones are composed of calcium oxalate, a concerted effort is to understand the pathophysiological aspects of high urinary oxalate excretion, considered an important risk factor in the development of kidney stones.

Currently, our researchers investigate:

  • Intestinal oxalate transport;
  • Immune response to viral infection;
  • The role of gastrointestinal bacterium, oxalobacter formigenes, in regulating oxalate homeostasis through catabolizing ingested oxalate; and
  • The relationship between oxalate-induced oxidative stress and kidney stone-induced inflammation of the kidney.

Related Faculty Members

 

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Stem Cell Research

The goal of the UF pathology researchers involved in stem cell biology is to understand the key mechanisms involved in stem cell activation, proliferation and differentiation. They work to define what role(s) stem cells may participate in gene delivery as a potential pathway in correcting inherent metabolic disorders and establish a cohesive collaborative research environment to refine basic research technologies that afford progression of this research toward clinical applications.


Related Faculty Members

Related Links

 

]]> http://pathology.ufl.edu/2012/07/15/experimental-pathology/feed/ 0 Forensic Medicine http://pathology.ufl.edu/2012/07/15/forensic-medicine/ http://pathology.ufl.edu/2012/07/15/forensic-medicine/#comments Sun, 15 Jul 2012 05:12:45 +0000 Angelo Biondini http://com-pathology.sites.medinfo.ufl.edu/?p=3772 The mission of the Forensic Medicine Division is fourfold – education, research, service and outreach. The Division utilizes its extensive expertise in forensic medicine to provide comprehensive services and innovative programs that relate to medicolegal death investigation, forensic toxicology and animal cruelty investigations. It also promotes efficient fiscal management and strategic future planning for growth and operational oversight; a visible presence for forensic medicine in the University of Florida  Department of Pathology, Immunology and Laboratory Medicine; the UF College of Medicine and the University; and increased interdisciplinary, cross-college and interagency communication and collaboration by providing a mechanism for promoting service, research, development, education and training.

In the execution of these functions, the Division operates five distinct service units, including:

  • District 8 Medical Examiner’s Office: The goal of the District 8 Medical Examiner’s Office is to provide forensic death investigation with scientific objectivity, irrespective of personal beliefs or emotional attachment to the circumstances of any particular case and shed light on any mysteries surrounding one’s death. We do this by performing thorough, impartial, objective forensic examinations of the body and circumstances surrounding every person’s demise to determine the cause and manner of death and to aid families, friends of the deceased and the justice system.
  • UF PathLabs’ Forensic Toxicology Laboratory: The primary mission of the Forensic Toxicology Laboratory is to support the Medical Examiner in the activity of investigating the cause and manner of death. In this regard, the Forensic Toxicology Laboratory provides comprehensive testing for the evaluation of the presence of poisons and/or exogenous chemicals (e.g., drugs and metabolites) in biological specimens provided as a function of the autopsy and/or inspection process. The findings are evaluated to determine what role, if any, they may have had in a given decedent’s death.
  • University of Florida Racing Laboratory: The Florida Racing Laboratory has provided drug testing services to the Florida Division of Pari-Mutuel Wagering for over sixty years and has been continuously accredited for animal drug testing and forensic toxicology under ISO 17025 since 2001.
  • Veterinary Forensic Sciences Program: This program is made possible with financial support from the American Society for the Prevention of Cruelty to Animals (ASPCA).  The program fosters the application of the forensic sciences to veterinary medicine through workshops, short courses, graduate research, case analysis, and distance education.
  • Florida Emergency Mortuary Operations Response System (FEMORS): The goal of FEMORS is to assist and support the local District Medical Examiner’s Office, Florida Department of Law Enforcement and other responding agencies in the event of a mass fatality incident, as directed by the Florida Department of Health.

Faculty

Collaborating Organizations

 
]]> http://pathology.ufl.edu/2012/07/15/forensic-medicine/feed/ 0 UF PathLabs http://pathology.ufl.edu/2012/07/15/uf-pathlabs/ http://pathology.ufl.edu/2012/07/15/uf-pathlabs/#comments Sun, 15 Jul 2012 05:11:12 +0000 Angelo Biondini http://com-pathology.sites.medinfo.ufl.edu/?p=902 University of Florida Pathology Laboratories (UF PathLabs) provides surgical pathology and diagnostic laboratory services for the Southeast United States. Headquartered in Gainesville, Florida, UF PathLabs has offered pathology services, testing, pathology second opinion services and autopsy services for more than 20 years. We serve all major markets across the state of Florida, including Jacksonville, Orlando and Tampa.

Home to more than 30 nationally recognized pathologists who are knowledgeable in all subspecialties of pathology, UF PathLabs has the expertise and experience to diagnose patient conditions quickly, accurately and professionally.

UF PathLabs is also a pathology instruction institution for UF College of Medicine residents and fellows, offering hands-on training from seasoned pathologists.

]]> http://pathology.ufl.edu/2012/07/15/uf-pathlabs/feed/ 0 Molecular Pathology Core http://molecular.pathology.ufl.edu/ http://molecular.pathology.ufl.edu/#comments Sun, 20 May 2012 19:49:22 +0000 Angelo Biondini http://com-pathology.sites.medinfo.ufl.edu/?p=986 The Molecular Pathology Core provides innovative and high-quality histology and immunolocalization services for basic and clinical research.

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