Clive H. Wasserfall, Ph.D.
|Assistant Professor||UF Department of Pathology, Immunology and Laboratory Medicine
College of Medicine
P.O. Box 100275
Gainesville, FL 32610
Office Location and Express Mail
Administrative Support AST I: Linda Harlan
Clive Wasserfall trained in clinical laboratory medicine in South Africa prior to pursuing graduate studies in the USA (MS) and Germany (PhD) focusing on clinical chemistry and immunology. My laboratory focus is on the immunopathogenesis of Type 1 Diabetes (T1D). Aspects of this work include refining prediction of disease onset/progression through the use of genetics, autoantibody assessment and other biomarkers.. We explore functional genomic, immunological and beta cell biological assays to gain mechanistic insight. We have expertise in the NOD mouse model of T1D and use this as a preclinical translation tool for mostly therapeutic experiments. Additionally, our laboratory is involved in immune monitoring of human clinical trails to reverse or prevent T1D while searching for biomarkers of efficacy. Our laboratory houses the screening autoantibody core for the JDRF network for pancreas organ donors with diabetes (nPOD) program. A recent development is our involvement in mapping normal human lymph nodes in 3D as part of the NIH HubMap consortium.