Allison M Andrews,
Associate Professor
Department:
MD-PATHOLOGY-GENERAL
Business Phone:
(352) 294-5275
Business Email:
andrews.allison@ufl.edu
Teaching Profile
Courses Taught
2024
GMS5905 Special Topics in Biomedical Sciences
Publications
Academic Articles
2024
Effects of Drag-Reducing Polymers on Hemodynamics and Whole Blood-Endothelial Interactions in 3D-Printed Vascular Topologies.
ACS applied materials & interfaces.
16(12):14457-14466
[DOI] 10.1021/acsami.3c17099.
[PMID] 38488736.
2024
Engineered Dual Antioxidant Enzyme Complexes Targeting ICAM-1 on Brain Endothelium Reduce Brain Injury-Associated Neuroinflammation.
Bioengineering (Basel, Switzerland).
11(3)
[DOI] 10.3390/bioengineering11030200.
[PMID] 38534474.
2024
Something to talk about; crosstalk disruption at the neurovascular unit during HIV infection of the CNS.
NeuroImmune pharmacology and therapeutics.
3(2):97-111
[DOI] 10.1515/nipt-2024-0003.
[PMID] 39958876.
2023
A Next-Generation 3D Tissue-Engineered Model of the Human Brain Microvasculature to Study the Blood-Brain Barrier.
Bioengineering (Basel, Switzerland).
10(7)
[DOI] 10.3390/bioengineering10070817.
[PMID] 37508844.
2023
Activation of CB2R by synthetic CB2R agonist, PM289, improves brain endothelial barrier properties, decreases inflammatory response and enhances endothelial repair.
NeuroImmune pharmacology and therapeutics.
2(4):387-400
[DOI] 10.1515/nipt-2023-0016.
[PMID] 38116176.
2023
An Engineered Adeno-Associated Virus Capsid Mediates Efficient Transduction of Pericytes and Smooth Muscle Cells of the Brain Vasculature.
Human gene therapy.
34(15-16):682-696
[DOI] 10.1089/hum.2022.211.
[PMID] 37376759.
2021
ErbB3 is a critical regulator of cytoskeletal dynamics in brain microvascular endothelial cells: Implications for vascular remodeling and blood brain barrier modulation.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
41(9):2242-2255
[DOI] 10.1177/0271678X20984976.
[PMID] 33583260.
2021
Extracellular Microvesicles Released From Brain Endothelial Cells are Detected in Animal Models Of HIV-1 Signifying Unresolved Inflammation.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.
16(4):785-795
[DOI] 10.1007/s11481-021-10008-5.
[PMID] 34435263.
2021
SARS-CoV-2 Spike Protein Disrupts Blood-Brain Barrier Integrity via RhoA Activation.
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology.
16(4):722-728
[DOI] 10.1007/s11481-021-10029-0.
[PMID] 34687399.
2021
The psychoactive drug of abuse mephedrone differentially disrupts blood-brain barrier properties.
Journal of neuroinflammation.
18(1)
[DOI] 10.1186/s12974-021-02116-z.
[PMID] 33648543.
2021
The Use of Tissue Engineering to Fabricate Perfusable 3D Brain Microvessels in vitro.
Frontiers in physiology.
12
[DOI] 10.3389/fphys.2021.715431.
[PMID] 34531761.
2020
Experimental Traumatic Brain Injury during Adolescence Enhances Cocaine Rewarding Efficacy and Dysregulates Dopamine and Neuroimmune Systems in Brain Reward Substrates.
Journal of neurotrauma.
37(1):27-42
[DOI] 10.1089/neu.2019.6472.
[PMID] 31347447.
2020
Reward and immune responses in adolescent females following experimental traumatic brain injury.
Behavioural brain research.
379
[DOI] 10.1016/j.bbr.2019.112333.
[PMID] 31682867.
2020
The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood-brain barrier.
Neurobiology of disease.
146
[DOI] 10.1016/j.nbd.2020.105131.
[PMID] 33053430.
2019
Endothelial Targeted Strategies to Combat Oxidative Stress: Improving Outcomes in Traumatic Brain Injury.
Frontiers in neurology.
10
[DOI] 10.3389/fneur.2019.00582.
[PMID] 31275220.
2018
Characterization of human fetal brain endothelial cells reveals barrier properties suitable for in vitro modeling of the BBB with syngenic co-cultures.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
38(5):888-903
[DOI] 10.1177/0271678X17708690.
[PMID] 28534661.
2018
Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers.
Fluids and barriers of the CNS.
15(1)
[DOI] 10.1186/s12987-018-0104-7.
[PMID] 29960602.
2017
Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury.
Scientific reports.
7(1)
[DOI] 10.1038/s41598-017-03309-4.
[PMID] 28630485.
2017
Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity.
Scientific reports.
7(1)
[DOI] 10.1038/s41598-017-03027-x.
[PMID] 28578388.
2017
Cholesterol Enrichment Impairs Capacitative Calcium Entry, eNOS Phosphorylation & Shear Stress-Induced NO Production.
Cellular and molecular bioengineering.
10(1):30-40
[DOI] 10.1007/s12195-016-0456-5.
[PMID] 28138348.
2017
Dexamethasone Attenuates the Enhanced Rewarding Effects of Cocaine Following Experimental Traumatic Brain Injury.
Cell transplantation.
26(7):1178-1192
[DOI] 10.1177/0963689717714341.
[PMID] 28933216.
2017
Trafficking of adeno-associated virus vectors across a model of the blood-brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells.
Journal of neurochemistry.
140(2):216-230
[DOI] 10.1111/jnc.13861.
[PMID] 27718541.
2016
Mechanical Injury Induces Brain Endothelial-Derived Microvesicle Release: Implications for Cerebral Vascular Injury during Traumatic Brain Injury.
Frontiers in cellular neuroscience.
10
[DOI] 10.3389/fncel.2016.00043.
[PMID] 26973460.
2016
Microparticle-Induced Activation of the Vascular Endothelium Requires Caveolin-1/Caveolae.
PloS one.
11(2)
[DOI] 10.1371/journal.pone.0149272.
[PMID] 26891050.
2016
Neuregulin1-β decreases interleukin-1β-induced RhoA activation, myosin light chain phosphorylation, and endothelial hyperpermeability.
Journal of neurochemistry.
136(2):250-7
[DOI] 10.1111/jnc.13374.
[PMID] 26438054.
2015
Identification and dynamic regulation of tight junction protein expression in human neural stem cells.
Stem cells and development.
24(12):1377-89
[DOI] 10.1089/scd.2014.0497.
[PMID] 25892136.
2014
Shear stress-induced NO production is dependent on ATP autocrine signaling and capacitative calcium entry.
Cellular and molecular bioengineering.
7(4):510-520
[PMID] 25386222.
2013
Fluid shear stress induces the clustering of heparan sulfate via mobility of glypican-1 in lipid rafts.
American journal of physiology. Heart and circulatory physiology.
305(6):H811-20
[DOI] 10.1152/ajpheart.00764.2012.
[PMID] 23851278.
2011
Glycated collagen alters endothelial cell actin alignment and nitric oxide release in response to fluid shear stress.
Journal of biomechanics.
44(10):1927-35
[DOI] 10.1016/j.jbiomech.2011.04.026.
[PMID] 21555127.
2010
Direct, real-time measurement of shear stress-induced nitric oxide produced from endothelial cells in vitro.
Nitric oxide : biology and chemistry.
23(4):335-42
[DOI] 10.1016/j.niox.2010.08.003.
[PMID] 20719252.
Grants
Sep 2024
ACTIVE
Neuroimmune and Cognitive Consequences of Nicotine Use in a Rodent Model of HIV: Implications for Anti-Retroviral Therapies
Role: Principal Investigator
Funding: UNIV OF KENTUCKY
via NATL INST OF HLTH NIDA
Jun 2024
ACTIVE
Synthetic fentanyls adversely affect the blood-brain barrier and HIV replication in the context of neuroHIV
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDA
Jun 2024
ACTIVE
Innovative In-Situ Imaging Techniques for the Visualization of CNS associated HIV reservoirs in the Context of Substance Abuse
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDA
Oct 2023
ACTIVE
HIV and Cocaine Drive Bone-Marrow Blood (BMB) Barrier Dysfunction and Altered Hematopoietic Stem Cell (HSC) Differentiation Leading to Cardiovascular Disease
Role: Principal Investigator
Funding: NATL INST OF HLTH NIDA
Sep 2023
ACTIVE
The role of cannabinoids in the regulation of the blood brain barrier in the context of NeuroHIV and anti-retroviral therapy
Role: Co-Investigator
Funding: TEMPLE UNIVERSITY
via NATL INST OF HLTH NIDA
Contact Details
Phones:
- Business:
- (352) 294-5275
Emails:
- Business:
- andrews.allison@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100275
GAINESVILLE FL 32610 - Business Street:
-
d6 18B Pathology
1395 Center Dr
Gainesville FL 32610