Ryan H Kolb

Ryan H Kolb,

AST PROF

Department: MD-PATHOLOGY-GENERAL
Business Phone: (352) 273-6834
Business Email: ryankolb@ufl.edu

Research Profile

Areas of Interest
  • Breast Cancers
  • Cancer
  • Cancer Immunotherapy
  • Inflammation
  • Obesity

Publications

2021
Proteolysis-targeting chimera against BCL-XL destroys tumor-infiltrating regulatory T cells.
Nature communications. 12(1) [DOI] 10.1038/s41467-021-21573-x. [PMID] 33627663.
2020
Cancer cell-intrinsic function of CD177 in attenuating β-catenin signaling.
Oncogene. 39(14):2877-2889 [DOI] 10.1038/s41388-020-1203-x. [PMID] 32042113.
2020
IL-1 Signaling in Tumor Microenvironment.
Advances in experimental medicine and biology. 1240:1-23 [DOI] 10.1007/978-3-030-38315-2_1. [PMID] 32060884.
2020
Obesity and Breast Cancer: A Case of Inflamed Adipose Tissue.
Cancers. 12(6) [DOI] 10.3390/cancers12061686. [PMID] 32630445.
2019
Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4.
Oncogene. 38(13):2351-2363 [DOI] 10.1038/s41388-018-0592-6. [PMID] 30518876.
2019
ROR1 Potentiates FGFR Signaling in Basal-Like Breast Cancer.
Cancers. 11(5) [DOI] 10.3390/cancers11050718. [PMID] 31137681.
2015
A novel function of HER2/Neu in the activation of G2/M checkpoint in response to γ-irradiation.
Oncogene. 34(17):2215-26 [DOI] 10.1038/onc.2014.167. [PMID] 24909175.
2012
ERK1/2 signaling plays an important role in topoisomerase II poison-induced G2/M checkpoint activation.
PloS one. 7(11) [DOI] 10.1371/journal.pone.0050281. [PMID] 23166842.
2012
RAC1 GTPase plays an important role in γ-irradiation induced G2/M checkpoint activation.
Breast cancer research : BCR. 14(2) [PMID] 22494620.
View on: PubMed
2010
Protein phosphatase 2A has an essential role in the activation of gamma-irradiation-induced G2/M checkpoint response.
Oncogene. 29(30):4317-29 [DOI] 10.1038/onc.2010.187. [PMID] 20498628.
2008
Gamma-irradiation-induced DNA damage checkpoint activation involves feedback regulation between extracellular signal-regulated kinase 1/2 and BRCA1.
Cancer research. 68(13):5113-21 [DOI] 10.1158/0008-5472.CAN-07-5818. [PMID] 18593910.
1991
Effects of atenolol alone, nifedipine alone and their combination on ambulant myocardial ischemia.
The American journal of cardiology. 67(8):671-5 [PMID] 2006616.
View on: PubMed

Grants

Mar 2020 ACTIVE
Targeting ANGPTL4 in obesity-driven breast cancer progression
Role: Principal Investigator
Funding: NATL INST OF HLTH NCI
Apr 2019 ACTIVE
Modulating Cancer Genetics for Immune Regulation and Breast Cancer Therapy
Role: Other
Funding: US ARMY MED RES ACQUISITION
Mar 2019 ACTIVE
CD177 suppresses breast-cancer development by inhibiting beta-catenin
Role: Co-Investigator
Funding: NATL INST OF HLTH NCI
Dec 2015 ACTIVE
Obesity, inflammation and breast cancer
Role: Co-Investigator
Funding: NATL INST OF HLTH NCI

Contact Details

Phones:
Business:
(352) 273-6834
Emails:
Business:
ryankolb@ufl.edu