Marino Leon

Marino Leon, MD, FCAP, FASCP

CLIN PROF

Department: MD-PATHOLOGY-GENERAL
Business Phone: (352) 627-9260
Business Email: marino.leon@ufl.edu

About Marino Leon

Specialty: Anatomic and Clinical Pathology

Subspecialty: Cytopathology

Board Certifications

  • Cytopathology
    American Board of Pathology
  • Pathology – Anatomical and Clinical
    American Board of Pathology

Research Profile

Clinical and translational research on Head and Neck tumors including thyroid tumors and HPV-related squamous cell carcinomas of the head and neck.

Open Researcher and Contributor ID (ORCID)

0000-0002-6457-7023

Areas of Interest
  • Cancer
  • Cytology
  • Oral cancer
  • Translational HPV Research

Publications

2021
Mucoacinar Carcinoma: A Rare Variant of Mucoepidermoid Carcinoma.
The American journal of surgical pathology. 45(8):1028-1037 [DOI] 10.1097/PAS.0000000000001752. [PMID] 34091485.
2021
Proliferative Verrucous Leukoplakia: An Expert Consensus Guideline for Standardized Assessment and Reporting.
Head and neck pathology. 15(2):572-587 [DOI] 10.1007/s12105-020-01262-9. [PMID] 33415517.
2020
Benign lesions of the mediastinum: A review with emphasis on cytology and small biopsy specimens.
Seminars in diagnostic pathology. 37(4):199-210 [DOI] 10.1053/j.semdp.2020.04.001. [PMID] 32534865.
2020
Immunohistochemical Expression of CDX2 and SATB2 in Primary Breast Carcinomas.
Applied immunohistochemistry & molecular morphology : AIMM. 28(6) [DOI] 10.1097/PAI.0000000000000748. [PMID] 30741745.
2020
Inter-observer Variability in the Diagnosis of Proliferative Verrucous Leukoplakia: Clinical Implications for Oral and Maxillofacial Surgeon Understanding: A Collaborative Pilot Study.
Head and neck pathology. 14(1):156-165 [DOI] 10.1007/s12105-019-01035-z. [PMID] 30972634.
2020
Ultrasound Detection of Human Botfly Myiasis of the Scalp: A Case Report.
Cureus. 12(12) [DOI] 10.7759/cureus.11905. [PMID] 33415056.
2019
Gastric Plexiform Fibromyxoma: A Great Mimic of Gastrointestinal Stromal Tumor (GIST) and Diagnostic Pitfalls.
The Journal of surgical research. 239:76-82 [DOI] 10.1016/j.jss.2019.01.062. [PMID] 30822694.
2018
An unusual case of chylothorax.
Respiratory medicine case reports. 25:318-322 [DOI] 10.1016/j.rmcr.2018.10.020. [PMID] 30402386.
2018
Clinical performance of endobronchial ultrasound-guided transbronchial needle aspiration for assessing programmed death ligand-1 expression in nonsmall cell lung cancer.
Diagnostic cytopathology. 46(5):378-383 [DOI] 10.1002/dc.23900. [PMID] 29476608.
2018
Impact of oncogene panel results on surgical management of cytologically indeterminate thyroid nodules.
Head & neck. 40(8):1812-1823 [DOI] 10.1002/hed.25165. [PMID] 29624786.
2017
A rare case of Epstein-Barr virus-related plasmacytoma involving maxillary sinus mucosa.
Clinical case reports. 5(9):1482-1485 [DOI] 10.1002/ccr3.959. [PMID] 28878909.
2017
Cancer Risk Stratification of Indeterminate Thyroid Nodules: A Cytological Approach.
Thyroid : official journal of the American Thyroid Association. 27(10):1277-1284 [DOI] 10.1089/thy.2017.0221. [PMID] 28806881.
2017
Evaluation of ThyroSeq v2 performance in thyroid nodules with indeterminate cytology.
Endocrine-related cancer. 24(3):127-136 [DOI] 10.1530/ERC-16-0512. [PMID] 28104680.
2017
Mammary Analog Secretory Carcinoma (MASC) Involving the Thyroid Gland: A Report of the First 3 Cases.
Head and neck pathology. 11(2):124-130 [DOI] 10.1007/s12105-016-0741-6. [PMID] 27400918.
2017
Multicentre validation of a microRNA-based assay for diagnosing indeterminate thyroid nodules utilising fine needle aspirate smears.
Journal of clinical pathology. 70(6):500-507 [DOI] 10.1136/jclinpath-2016-204089. [PMID] 27798083.
2017
Regarding Bocklage et al. “Regarding Dettloff et al. Mammary Analog Secretory Carcinoma (MASC) Involving the Thyroid Gland: A Report of First 3 Cases”.
Head and neck pathology. 11(2):266-267 [DOI] 10.1007/s12105-016-0756-z. [PMID] 27644952.
2016
Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue.
Oncotarget. 7(12):14605-15 [DOI] 10.18632/oncotarget.7522. [PMID] 26910279.
2016
Diagnostic Challenges in the Fine Needle Aspiration Biopsy of Chronic Sclerosing Sialadenitis (K├╝ttner’s Tumor) in the Context of Head and Neck Malignancy: A Series of 4 Cases.
Head and neck pathology. 10(3):389-93 [DOI] 10.1007/s12105-016-0701-1. [PMID] 26909791.
2016
Hypermetabolism on (18)F-Fluorodeoxyglucose Positron Emission Tomography Scan Does Not Influence the Interpretation of Thyroid Cytopathology, and Nodules with a SUVmax
Thyroid : official journal of the American Thyroid Association. 26(9):1300-7 [DOI] 10.1089/thy.2015.0654. [PMID] 27324615.
2016
Institutional prevalence of malignancy of indeterminate thyroid cytology is necessary but insufficient to accurately interpret molecular marker tests.
European journal of endocrinology. 174(5):621-9 [DOI] 10.1530/EJE-15-1163. [PMID] 26903551.
2016
Low-Grade Fibromyxoid Sarcoma of the Head and Neck: A Clinicopathologic Series and Review of the Literature.
Head and neck pathology. 10(2):161-6 [DOI] 10.1007/s12105-015-0647-8. [PMID] 26276044.
2016
Pathology Report: Presacral Noncommunicating Enteric Duplication Cyst
Cancer Control. 23(2):170-174 [DOI] 10.1177/107327481602300213. [PMID] 27218796.
2016
Salivary Duct Carcinoma of the Parotid: Outcomes with a Contemporary Multidisciplinary Treatment Approach.
Otolaryngology–head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 154(6):1041-6 [DOI] 10.1177/0194599816636812. [PMID] 26980918.
2016
Sinonasal small round blue cell tumors: An approach to diagnosis.
Seminars in diagnostic pathology. 33(2):91-103 [DOI] 10.1053/j.semdp.2015.09.010. [PMID] 26585346.
2016
Surgical management of oropharyngeal squamous cell carcinoma: Survival and functional outcomes.
Head & neck. 38 Suppl 1:E1794-802 [DOI] 10.1002/hed.24319. [PMID] 26694981.
2015
A randomized phase II efficacy and correlative studies of cetuximab with or without sorafenib in recurrent and/or metastatic head and neck squamous cell carcinoma.
Oral oncology. 51(4):376-82 [DOI] 10.1016/j.oraloncology.2014.12.011. [PMID] 25593015.
2015
Human papillomavirus-related squamous cell carcinoma of the anal canal with papillary features.
World journal of gastroenterology. 21(7):2210-3 [DOI] 10.3748/wjg.v21.i7.2210. [PMID] 25717259.
2015
Inter- and intra-observer variability in the classification of extracapsular extension in p16 positive oropharyngeal squamous cell carcinoma nodal metastases.
Oral oncology. 51(11):985-990 [DOI] 10.1016/j.oraloncology.2015.08.003. [PMID] 26293844.
2015
Molecular Assays in Cytopathology for Thyroid Cancer.
Cancer control : journal of the Moffitt Cancer Center. 22(2):152-7 [PMID] 26068759.
View on: PubMed
2014
A woman with swelling of the posterior pharyngeal wall.
JAMA otolaryngology– head & neck surgery. 140(7):671-2 [DOI] 10.1001/jamaoto.2014.861. [PMID] 24902797.
2014
Metastatic squamous cell carcinoma of the anus to the lung confirmed with allelotyping.
Case reports in pathology. 2014 [DOI] 10.1155/2014/608521. [PMID] 24660084.
2013
Altruism in terminal cancer patients and rapid tissue donation program: does the theory apply?
. 16(4):857-864
2013
Altruism in terminal cancer patients and rapid tissue donation program: does the theory apply?
Medicine, health care, and philosophy. 16(4):857-64 [DOI] 10.1007/s11019-013-9480-6. [PMID] 23539332.
2013
Assessment of FANCD2 nuclear foci formation in paraffin-embedded tumors: a potential patient-enrichment strategy for treatment with DNA interstrand crosslinking agents
Translational Research. 161(3):156-164 [DOI] 10.1016/j.trsl.2012.09.003. [PMID] 23063585.
2013
Chondromyxoid fibroma of the nasal septum: case report and review of literature.
Head & neck. 35(1):E1-5 [DOI] 10.1002/hed.21760. [PMID] 21544896.
2013
Chondrosarcoma of the subglottic larynx: submucosal microdissection with the operating microscope.
The Laryngoscope. 123(5):1216-9 [DOI] 10.1002/lary.23957. [PMID] 23404226.
2013
Diagnostic digital cytopathology: Are we ready yet?
Journal of pathology informatics. 4 [DOI] 10.4103/2153-3539.120727. [PMID] 24392242.
2013
Transcription factor ATF3 links host adaptive response to breast cancer metastasis.
The Journal of clinical investigation. 123(7):2893-906 [DOI] 10.1172/JCI64410. [PMID] 23921126.
2012
Altered p16(INK4) and RB1 Expressions Are Associated with Poor Prognosis in Patients with Nonsmall Cell Lung Cancer.
Journal of oncology. 2012 [DOI] 10.1155/2012/957437. [PMID] 22619677.
2011
Aggressive osteoblastoma of the maxilla: a case report and review of the literature.
Head and neck pathology. 5(2):165-70 [DOI] 10.1007/s12105-010-0234-y. [PMID] 21181315.
2011
Trabecular and psammomatoid juvenile ossifying fibroma of the skull base mimicking psammomatoid meningioma.
Head and neck pathology. 5(1):71-5 [DOI] 10.1007/s12105-010-0212-4. [PMID] 20953744.
2010
Comparative mutational profiling in the assessment of lung lesions: should it be the standard of care?
The Annals of thoracic surgery. 90(2):388-96 [DOI] 10.1016/j.athoracsur.2010.03.059. [PMID] 20667316.
2010
Correlation between Mcl-1 and pAKT protein expression in colorectal cancer.
International journal of clinical and experimental pathology. 3(8):768-74 [PMID] 21151390.
View on: PubMed
2010
Idiopathic hypertrophic pyloric stenosis in an adult, a potential mimic of gastric carcinoma
Pathology research international. 2010 [DOI] 10.4061/2010/614280. [PMID] 21151511.
2009
Metastatic squamous cell carcinoma of the vulva to the lung confirmed with allelotyping.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. 28(5):497-501 [DOI] 10.1097/PGP.0b013e3181a23c6c. [PMID] 19696623.
2009
Multiple neuroenteric cysts at cerebello-pontine angle and foramen magnum: a case report and review of the literature.
Neuropathology : official journal of the Japanese Society of Neuropathology. 29(3):318-22 [DOI] 10.1111/j.1440-1789.2008.00958.x. [PMID] 18715273.
2009
Prospective evaluation of DNA mismatch repair protein expression in primary endometrial cancer.
Gynecologic oncology. 114(3):486-90 [DOI] 10.1016/j.ygyno.2009.05.026. [PMID] 19515405.
2009
Tumor-to-tumor metastasis: Renal cell carcinoma metastatic to papillary carcinoma of thyroid-report of a case and review of the literature.
Head and neck pathology. 3(4):327-30 [DOI] 10.1007/s12105-009-0147-9. [PMID] 20596854.
2007
Pathobiology of small invasive breast cancers without metastases (T1a/b, N0, M0): National Surgical Adjuvant Breast and Bowel Project (NSABP) protocol B-21
Cancer. 110(9):1929-1936 [DOI] 10.1002/cncr.23011. [PMID] 17896781.
2006
Critical values in cytology.
Diagnostic cytopathology. 34(6):447-51 [PMID] 16680772.
View on: PubMed
2004
Fine-needle aspiration of adult small-round-cell tumors studied with flow cytometry.
Diagnostic cytopathology. 31(3):147-54 [PMID] 15349982.
View on: PubMed
2003
Carcinoembryonic antigen elevation due to bowel sequestration with mucocele formation following colonic resection
Archives of Pathology & Laboratory Medicine. 127(10):1376-1379 [DOI] 10.1043/1543-2165(2003)127<1376:CAEDTB>2.0.CO;2. [PMID] 14521450.
2003
Pathologic quiz case: A localized pulmonary consolidation in a young woman
Archives of Pathology & Laboratory Medicine. 127(1):e49-e50 [DOI] 10.1043/0003-9985(2003)127<e49:PQCLPC>2.0.CO;2. [PMID] 12562299.
2003
Polymorphous low-grade adenocarcinoma of the vulva and vagina: a tumor resembling adenoid cystic carcinoma
International Journal of Surgical Pathology. 11(1):43-49 [DOI] 10.1177/106689690301100113. [PMID] 12598921.
2002
Cholesterol Granuloma of the Maxillary Sinus
Archives of Pathology & Laboratory Medicine. 126(2):217-219 [DOI] 10.1043/0003-9985(2002)126<0217:CGOTMS>2.0.CO;2. [PMID] 11825124.
2002
Fine needle aspiration diagnosis of lipoblastoma of the parotid region. A case report.
Acta cytologica. 46(2):395-404 [PMID] 11917592.
View on: PubMed
2002
Nodular myofibroblastic stromal hyperplasia of the mammary gland as an accurate name for pseudoangiomatous stromal hyperplasia of the mammary gland
Breast Journal. 8(5):290-293 [DOI] 10.1046/j.1524-4741.2002.08508.x. [PMID] 12199757.
2002
Pathologic Quiz Case. Systemic Symptoms in a Human Immunodeficiency Virus Type 1-positive 30-year-old Man
Archives of Pathology & Laboratory Medicine. 126(4):495-496 [DOI] 10.1043/0003-9985(2002)126<0495:PQCSSI>2.0.CO;2. [PMID] 11900584.

Grants

Jun 2019 ACTIVE
OR-DRPD-ROF2019: Rapid Detection of Cerebrospinal Fluid and Development of a Modular Point of Care Testing Solution with Low-Cost Disposable Testing Strips
Role: Co-Investigator
Funding: UF RESEARCH

Education

Fellowship – Hematopathology
2001 · Allegheny General Hospital
Fellowship – Cytopathology
2000 · Hahnemann University Hospital
Residency – Pathology – Anatomic and Clinical
2000 · Hahnemann University Hospital
Fellowship – Pathology
1999 · Hahnemann University Hospital
Residency – Pathology – Anatomic and Clinical
1998 · Cook County Hospital
Medical Degree
1990 · Universidad Peruana Cayetano Heredia

Teaching Profile

Courses Taught
2018
MDT7530 Elect Top/Pathology

Contact Details

Phones:
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(352) 627-9260
Emails:
Office Manager:
Karen E Hyde
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