Carla N Mavian,
Assistant Professor
About Carla N Mavian
I obtained my bachelor and master in biotechnology from University of Padova, Italy. I obtained my PhD in the Centro de Biología Molecular Severo Ochoa hosted at the Autonomous University of Madrid, Spain, mentored by Dr. Antonio Alcami. My PhD focused on evolution and immunodynamics of poxviruses. I joined the University of Florida during my postdoctoral training mentored by Dr. Maureen Goodenow and Dr. Marco Salemi.
Accomplishments
Assistant Professor
2023
·
University of Florida
Mentor
2020
·
University Multicultural Mentor Program
Co-organizer
2019-Current
·
International Bioinformatics Workshop on Virus Evolution and Molecular Epidemiology
Software & Data Carpentry Certified Instructor
2019-Current
·
Data Carpentry
Research Assistant Scientist
2019-2023
·
University of Florida
Board Member
2019
·
UF Carpentries Club
Instructor
2018-Current
·
International Bioinformatics Workshop on Virus Evolution and Molecular Epidemiology
Thomas H. Maren Awardee
2017-2019
·
UF College of Medicine
Young Investigator Award
2017
·
American Society of Tropical Medicine and Hygiene
Young Investigator Award
2015
·
Conference of Retrovirology and Opportunistic Infections
Postdoctoral Associate
2014-2019
·
University of Florida
Teaching Profile
Courses Taught
2024
PHC6722 Environmental and Global Health Research Methods Rotation
2024
GMS6140 Principles of Immunology
Research Profile
My research program supports cross-disciplinary approaches to the study of infectious diseases. My area of research is infectious diseases, with emphasis on molecular evolution and host-pathogen interactions. My research spans from large-scale epidemic processes, such as population growth and spatial epidemic dispersal, to small-scale transmission histories; and within-host evolution, including adaptation and recombination. My Google Scholar profile: https://scholar.google.com/citations?user=1nPwPo4AAAAJ&hl=en&oi=ao
Open Researcher and Contributor ID (ORCID)
0000-0003-3819-5520
Publications
2024
Oral Cannabidiol Treatment Is Associated with an Anti-Inflammatory Gene Expression Signature in Myeloid Cells of People Living with HIV
Cannabis and Cannabinoid Research.
[DOI] 10.1089/can.2023.0139.
2023
Ancestral Origin and Dissemination Dynamics of Reemerging Toxigenic Vibrio cholerae, Haiti.
Emerging infectious diseases.
29(10):2072-2082
[DOI] 10.3201/eid2910.230554.
[PMID] 37735743.
2023
Application of Phylodynamic Tools to Inform the Public Health Response to COVID-19: Qualitative Analysis of Expert Opinions
JMIR Formative Research.
7
[DOI] 10.2196/39409.
[PMID] 36848460.
2023
ARCA: the interactive database for arbovirus reported cases in the Americas.
BMC bioinformatics.
24(1)
[DOI] 10.1186/s12859-023-05433-7.
[PMID] 37587443.
2023
Genetic Characterization of a Novel Equus caballus Papillomavirus Isolated from a Thoroughbred Mare
Viruses.
15(3)
[DOI] 10.3390/v15030650.
[PMID] 36992359.
2023
Genomic Epidemiology and Lineage Dynamics of SARS-CoV-2 in Bulgaria: Insights from a Three-Year Pandemic Analysis
Viruses.
15(9)
[DOI] 10.3390/v15091924.
[PMID] 37766330.
2023
Infectivity of three Mayaro Virus geographic isolates in human cell lines.
Acta tropica.
242
[DOI] 10.1016/j.actatropica.2023.106894.
[PMID] 36965613.
2023
Molecular Basis of the Toxigenic Vibrio cholerae O1 Serotype Switch from Ogawa to Inaba in Haiti
Microbiology Spectrum.
11(1)
[DOI] 10.1128/spectrum.03624-22.
[PMID] 36537825.
2023
Persistence of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant in Children and Utility of Rapid Antigen Testing as an Indicator of Culturable Virus.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
76(3):e491-e494
[DOI] 10.1093/cid/ciac693.
[PMID] 36029095.
2023
Seafood-Associated Outbreak of ctx-Negative Vibrio mimicus Causing Cholera-Like Illness, Florida, USA.
Emerging infectious diseases.
29(10):2141-2144
[DOI] 10.3201/eid2910.230486.
[PMID] 37735754.
2023
The panzootic potential of SARS-CoV-2
BioScience.
73(11):814-829
[DOI] 10.1093/biosci/biad102.
[PMID] 38125826.
2022
Analysis of the Origin and Dissemination of HIV-1 Subtype C in Bulgaria
Viruses.
14(2)
[DOI] 10.3390/v14020263.
[PMID] 35215855.
2022
Analysis of Zika Virus Sequence Data Associated with a School Cohort in Haiti.
The American journal of tropical medicine and hygiene.
107(4):873-880
[DOI] 10.4269/ajtmh.22-0204.
[PMID] 36096408.
2022
Discordance between HIV-1 Population in Plasma at Rebound after Structured Treatment Interruption and Archived Provirus Population in Peripheral Blood Mononuclear Cells.
Microbiology spectrum.
10(4)
[DOI] 10.1128/spectrum.01353-22.
[PMID] 35699458.
2022
Emergence and Evolutionary Response of Vibrio cholerae to Novel Bacteriophage, Democratic Republic of the Congo1.
Emerging infectious diseases.
28(12):2482-2490
[DOI] 10.3201/eid2812.220572.
[PMID] 36417939.
2022
Everglades virus evolution: Genome sequence analysis of the envelope 1 protein reveals recent mutation and divergence in South Florida wetlands
Virus Evolution.
8(2)
[DOI] 10.1093/ve/veac111.
[PMID] 36582503.
2022
Genome Sequence of Genotype 1A Hepatovirus A Isolated from Plasma from a Haitian Child.
Microbiology resource announcements.
11(9)
[DOI] 10.1128/mra.00449-22.
[PMID] 35950865.
2022
Genomic Sequencing and Phylogenomics of Cowpox Virus
Viruses.
14(10)
[DOI] 10.3390/v14102134.
[PMID] 36298689.
2022
Isolation of a Novel Recombinant Canine Coronavirus From a Visitor to Haiti: Further Evidence of Transmission of Coronaviruses of Zoonotic Origin to Humans.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
75(1):e1184-e1187
[DOI] 10.1093/cid/ciab924.
[PMID] 34718467.
2022
Low‐frequency variants in mildly symptomatic vaccine breakthrough infections presents a doubled‐edged sword
Journal of Medical Virology.
94(7):3192-3202
[DOI] 10.1002/jmv.27726.
[PMID] 35307848.
2022
Molecular Epidemiology of HIV-1 Subtype B Infection across Florida Reveals Few Large Superclusters with Metropolitan Origin
Microbiology Spectrum.
10(6)
[DOI] 10.1128/spectrum.01889-22.
[PMID] 36222706.
2022
Optimizing viral genome subsampling by genetic diversity and temporal distribution (TARDiS) for phylogenetics.
Bioinformatics (Oxford, England).
38(3):856-860
[DOI] 10.1093/bioinformatics/btab725.
[PMID] 34672334.
2022
Rapid Emergence and Spread of Severe Acute Respiratory Syndrome Coronavirus 2 Gamma (P.1) Variant in Haiti.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
74(11):2057-2060
[DOI] 10.1093/cid/ciab736.
[PMID] 34471930.
2022
Rapid SARS-CoV-2 diagnosis using disposable strips and a metal-oxide-semiconductor field-effect transistor platform.
Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B.
40(2)
[DOI] 10.1116/6.0001615.
[PMID] 36032199.
2022
Severe Acute Respiratory Syndrome Coronavirus 2 Delta Vaccine Breakthrough Transmissibility in Alachua County, Florida.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
75(9):1618-1627
[DOI] 10.1093/cid/ciac197.
[PMID] 35271704.
2022
Structural Evolution of Delta (B.1.617.2) and Omicron (BA.1) Spike Glycoproteins
International Journal of Molecular Sciences.
23(15)
[DOI] 10.3390/ijms23158680.
[PMID] 35955815.
2021
Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis and poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets.
Journal of neurovirology.
27(1):101-115
[DOI] 10.1007/s13365-020-00927-z.
[PMID] 33405206.
2021
Comparative Pathogenesis, Genomics and Phylogeography of Mousepox
Viruses.
13(6)
[DOI] 10.3390/v13061146.
[PMID] 34203773.
2021
Comparison of SARS-CoV-2 Receptors Expression in Primary Endothelial Cells and Retinoic Acid-Differentiated Human Neuronal Cells
Viruses.
13(11)
[DOI] 10.3390/v13112193.
[PMID] 34834998.
2021
Emergence of porcine delta-coronavirus pathogenic infections among children in Haiti through independent zoonoses and convergent evolution.
medRxiv : the preprint server for health sciences.
[DOI] 10.1101/2021.03.19.21253391.
[PMID] 33791709.
2021
Independent infections of porcine deltacoronavirus among Haitian children
Nature.
600(7887):133-137
[DOI] 10.1038/s41586-021-04111-z.
[PMID] 34789872.
2021
Molecular Docking-Based Screening for Novel Inhibitors of the Human Immunodeficiency Virus Type 1 Protease that Effectively Reduce the Viral Replication in Human Cells.
Journal of AIDS & clinical research.
12(5)
[PMID] 34950525.
2021
Persistent HIV-1 transcription in CD4+ T cells from ART-suppressed individuals can originate from biologically competent proviruses.
Journal of virus eradication.
7(3)
[DOI] 10.1016/j.jve.2021.100053.
[PMID] 34621530.
2021
Sociodemographic, Ecological, and Spatiotemporal Factors Associated with Human Immunodeficiency Virus Drug Resistance in Florida: A Retrospective Analysis.
The Journal of infectious diseases.
223(5):866-875
[DOI] 10.1093/infdis/jiaa413.
[PMID] 32644119.
2021
The central role of Italy in the spatial spread of USUTU virus in Europe.
Virus evolution.
7(1)
[DOI] 10.1093/ve/veab048.
[PMID] 34513027.
2021
Trophic transfer and toxicity of heavy metals from dengue mosquito Aedes aegypti to predator dragonfly Tramea cophysa.
Ecotoxicology (London, England).
30(6):1108-1115
[DOI] 10.1007/s10646-021-02448-9.
[PMID] 34165678.
2020
A minor population of macrophage-tropic HIV-1 variants is identified in recrudescing viremia following analytic treatment interruption
Proceedings of the National Academy of Sciences.
117(18):9981-9990
[DOI] 10.1073/pnas.1917034117.
[PMID] 32300019.
2020
A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis
JMIR Public Health and Surveillance.
6(2)
[DOI] 10.2196/19170.
[PMID] 32412415.
2020
Authors’ Reply to: Errors in Tracing Coronavirus SARS-CoV-2 Transmission Using a Maximum Likelihood Tree. Comment on “A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis”
JMIR Public Health and Surveillance.
6(4)
[DOI] 10.2196/24661.
[PMID] 33174844.
2020
Collection of SARS-CoV-2 Virus from the Air of a Clinic Within a University Student Health Care Center and Analyses of the Viral Genomic Sequence.
Aerosol and air quality research.
20(6):1167-1171
[DOI] 10.4209/aaqr.2020.02.0202.
[PMID] 33424954.
2020
Correction: A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis
JMIR Public Health and Surveillance.
6(3)
[DOI] 10.2196/22853.
[PMID] 32776889.
2020
Differing impacts of global and regional responses on SARS-CoV-2 transmission cluster dynamics.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2020.11.06.370999.
[PMID] 33173870.
2020
Employing Molecular Phylodynamic Methods to Identify and Forecast HIV Transmission Clusters in Public Health Settings: A Qualitative Study.
Viruses.
12(9)
[DOI] 10.3390/v12090921.
[PMID] 32842636.
2020
Multiple Recombination Events and Strong Purifying Selection at the Origin of SARS-CoV-2 Spike Glycoprotein Increased Correlated Dynamic Movements
International Journal of Molecular Sciences.
22(1)
[DOI] 10.3390/ijms22010080.
[PMID] 33374797.
2020
Sampling bias and incorrect rooting make phylogenetic network tracing of SARS-COV-2 infections unreliable
Proceedings of the National Academy of Sciences.
117(23):12522-12523
[DOI] 10.1073/pnas.2007295117.
[PMID] 32381734.
2020
Toxigenic Vibrio cholerae evolution and establishment of reservoirs in aquatic ecosystems
Proceedings of the National Academy of Sciences.
117(14):7897-7904
[DOI] 10.1073/pnas.1918763117.
[PMID] 32229557.
2020
Under-the-Radar Dengue Virus Infections in Natural Populations of Aedes aegypti Mosquitoes.
mSphere.
5(2)
[DOI] 10.1128/mSphere.00316-20.
[PMID] 32350095.
2019
Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016.
PLoS neglected tropical diseases.
13(1)
[DOI] 10.1371/journal.pntd.0006972.
[PMID] 30629592.
2019
Isolation of Mayaro Virus from a Venezuelan Patient with Febrile Illness, Arthralgias, and Rash: Further Evidence of Regional Strain Circulation and Possible Long-Term Endemicity.
The American journal of tropical medicine and hygiene.
101(6):1219-1225
[DOI] 10.4269/ajtmh.19-0357.
[PMID] 31595869.
2019
Mayaro as a Caribbean traveler: Evidence for multiple introductions and transmission of the virus into Haiti.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
87:151-153
[DOI] 10.1016/j.ijid.2019.07.031.
[PMID] 31382049.
2018
A new “American” subgroup of African-lineage Chikungunya virus detected in and isolated from mosquitoes collected in Haiti, 2016.
PloS one.
13(5)
[DOI] 10.1371/journal.pone.0196857.
[PMID] 29746539.
2018
Detection and phylogenetic characterization of arbovirus dual-infections among persons during a chikungunya fever outbreak, Haiti 2014.
PLoS neglected tropical diseases.
12(5)
[DOI] 10.1371/journal.pntd.0006505.
[PMID] 29851952.
2018
Distribution and characterization of Shiga toxin converting temperate phages carried by Shigella flexneri in Hispaniola.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.
65:321-328
[DOI] 10.1016/j.meegid.2018.07.038.
[PMID] 30075254.
2018
Islands as Hotspots for Emerging Mosquito-Borne Viruses: A One-Health Perspective.
Viruses.
11(1)
[DOI] 10.3390/v11010011.
[PMID] 30585228.
2018
Madariaga Virus: Identification of a Lineage III Strain in a Venezuelan Child With Acute Undifferentiated Febrile Illness, in the Setting of a Possible Equine Epizootic.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
67(4):619-621
[DOI] 10.1093/cid/ciy224.
[PMID] 29718127.
2017
Emergence of recombinant Mayaro virus strains from the Amazon basin.
Scientific reports.
7(1)
[DOI] 10.1038/s41598-017-07152-5.
[PMID] 28821712.
2017
Fatal Systemic Salmonellosis in a Florida Manatee ( Trichechus manatus latirostris).
Journal of wildlife diseases.
53(4):930-933
[DOI] 10.7589/2017-01-012.
[PMID] 28463629.
2017
Phylodynamic applications in 21st century global infectious disease research.
Global health research and policy.
2
[DOI] 10.1186/s41256-017-0034-y.
[PMID] 29202081.
2017
Ranavirus phylogenomics: Signatures of recombination and inversions among bullfrog ranaculture isolates.
Virology.
511:330-343
[DOI] 10.1016/j.virol.2017.07.028.
[PMID] 28803676.
2016
Concurrence of Iridovirus, Polyomavirus, and a Unique Member of a New Group of Fish Papillomaviruses in Lymphocystis Disease-Affected Gilthead Sea Bream
Journal Of Virology.
90(19):8768-8779
[DOI] 10.1128/JVI.01369-16.
2014
Genome Sequence of WAU86/88-1, a New Variant of Vaccinia Virus Lister Strain from Poland.
Genome announcements.
2(1)
[DOI] 10.1128/genomeA.01086-13.
[PMID] 24407630.
2014
The genome sequence of ectromelia virus Naval and Cornell isolates from outbreaks in North America
Virology.
462-463:218-226
[DOI] 10.1016/j.virol.2014.06.010.
[PMID] 24999046.
2012
Complete genome sequence of the European sheatfish virus.
Journal of virology.
86(11):6365-6
[DOI] 10.1128/JVI.00618-12.
[PMID] 22570241.
2012
The genome sequence of the emerging common midwife toad virus identifies an evolutionary intermediate within ranaviruses.
Journal of virology.
86(7):3617-25
[DOI] 10.1128/JVI.07108-11.
[PMID] 22301140.
2009
Presentation of cytosolically stable peptides by HLA-B27 is not dependent on the canonic interactions of N-terminal basic residues in the A pocket.
Journal of immunology (Baltimore, Md. : 1950).
182(1):446-55
[PMID] 19109176.
A snapshot of SARS-CoV-2 genome availability up to 30thMarch, 2020 and its implications
.
[DOI] 10.1101/2020.04.01.020594.
A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis (Preprint)
.
[DOI] 10.2196/preprints.19170.
Authors’ Reply to: Errors in Tracing Coronavirus SARS-CoV-2 Transmission Using a Maximum Likelihood Tree. Comment on “A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis” (Preprint)
.
[DOI] 10.2196/preprints.24661.
Brain tissue transcriptomic analysis of SIV-infected macaques identifies Poly (ADP-ribose) polymerases (PARPs) as potential biomarkers for neuropathogenesis.
.
[DOI] 10.21203/rs.3.rs-30629/v1.
Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis, and Poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets
.
[DOI] 10.1101/2020.05.21.109140.
Correction: A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis (Preprint)
.
[DOI] 10.2196/preprints.22853.
Recombination and purifying selection preserves covariant movements of mosaic SARS-CoV-2 protein S
.
[DOI] 10.1101/2020.03.30.015685.
Grants
Mar 2024
ACTIVE
Aligning climate and health: assessing zoonotic arboviral risks in agroforestry as a climate mitigation strategy
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAID
Dec 2023
ACTIVE
Evolution, antimicrobial resistance, and virulence determinants of V. parahaemolyticus in aquatic birds and environments in Thailand
Role: Principal Investigator
Funding: CRDF GLOBAL
May 2023
ACTIVE
Defining a Role for Liver Myeloid Cells in Viral Persistence under ART
Role: Co-Investigator
Funding: UNIV OF MIAMI
via NATL INST OF HLTH NIDDK
Jul 2022
ACTIVE
A Phylodynamic Artificial Intelligence framework to predict evolution of SARS-CoV-2 variants of concern in Immunocompromised persons with HIV (PhAI-CoV)
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAID
May 2020
ACTIVE
Forecasting trajectories of HIV transmission networks with a novel phylodynamic and deep learning framework
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAID
Apr 2020
– Mar 2023
RAPID: Dynamic Identification of SARS-COV-2 Transmission Epicenters in Presence of Spatial Heterogeneity (COV-DYNAMITE)
Role: Co-Investigator
Funding: NATL SCIENCE FOU
Apr 2017
– Mar 2019
Salivary microRNA as novel biomarkers of HIV/AIDS disease progression in people living with HIV.
Role: Principal Investigator
Funding: UF FOUNDATION
Education
Postdoctoral Research
2014-2018
·
University of Florida
PhD
2013
·
Universidad Autonoma de Madrid
Contact Details
Phones:
- Business:
- (352) 273-5702
Emails:
- Business:
- cmavian@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100275
GAINESVILLE FL 32610 - Business Street:
-
1600 SW ARCHER RD
GAINESVILLE FL 32610