M Zehra Z Ordulu Sahin

M Zehra Z Ordulu Sahin,

CLIN AST PROF

Department: MD-PATHOLOGY-GENERAL
Business Phone: (352) 627-9240
Business Email: mordulusahin@ufl.edu

About M Zehra Z Ordulu Sahin

Dr Ordulu’s academic interests include: 1) Studying clinicopathological characteristics of gynecological tract tumors 2) Integrating different layers of molecular “omics” data into the practice of gynecologic pathology. With a background combining a strong training in anatomic pathology and a long-standing experience in molecular genetics, her long-term goals are to continue to integrate the two fields to transform the gynecologic pathology diagnostics into the era of precision medicine.

Accomplishments

Gynecologic Oncology Fellowship Teaching Award
2020 · Massachusetts General Hospital
Featured Women Researcher
2014 · Brigham and Women's Hospital
Research Excellence Award
2014 · Brigham and Women's Hospital
Charles J. Epstein Trainee Award for Excellence in Human Genetics Research – Finalist
2012 · American Society of Human Genetics
Featured Women Researcher
2012 · Brigham and Women's Hospital
Research Excellence Award
2012 · Brigham and Women's Hospital

Board Certifications

  • Combined Anatomic Pathology & Clinical Pathology Certification (AP/CP)
    American Board of Pathology
  • ECFMG
    Educational Commission For Foreign Medical Graduates

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0002-3218-1075

Publications

2021
Case 9-2021: A 16-Year-Old Boy with Headache, Abdominal Pain, and Hypertension.
The New England journal of medicine. 384(12):1145-1155 [DOI] 10.1056/NEJMcpc2027094. [PMID] 33761211.
2021
Deranged chromatin drives uterine fibroid tumours.
Nature. 596(7872):349-351 [DOI] 10.1038/d41586-021-02005-8. [PMID] 34349270.
2021
Embryonal rhabdomyosarcoma of the uterine corpus: a clinicopathological and molecular analysis of 21 cases highlighting a frequent association with DICER1 mutations.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. [DOI] 10.1038/s41379-021-00821-x. [PMID] 34017064.
2021
Innovating Evaluation and Treatment of Intrapartum Fevers: Where Do We Go from Here?
American journal of perinatology. [DOI] 10.1055/s-0041-1727279. [PMID] 33878764.
2021
Locally Recurrent Secretory Carcinoma of the Breast with NTRK3 Gene Fusion.
The oncologist. [DOI] 10.1002/onco.13880. [PMID] 34176200.
2021
Low-grade Endometrial Stromal Sarcoma With Sex Cord-like Differentiation and PHF1-JAZF1 Fusion With Deletions: A Diagnostic Pitfall of JAZF1 FISH.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists. [DOI] 10.1097/PGP.0000000000000795. [PMID] 34074959.
2021
Molecular Pathology of Ovarian Epithelial Neoplasms: Predictive, Prognostic, and Emerging Biomarkers.
Surgical pathology clinics. 14(3):415-428 [DOI] 10.1016/j.path.2021.05.006. [PMID] 34373093.
2021
Reproducibility of scoring criteria for HER2 immunohistochemistry in endometrial serous carcinoma: a multi-institutional interobserver agreement study.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 34(6):1194-1202 [DOI] 10.1038/s41379-021-00746-5. [PMID] 33536574.
2021
Sertoli-Leydig Cell Tumors of the Ovary With Follicular Differentiation Often Resembling Juvenile Granulosa Cell Tumor: A Report of 38 Cases Including Comments on Sex Cord-Stromal Tumors of Mixed Forms (So-called Gynandroblastoma).
The American journal of surgical pathology. 45(1):59-67 [DOI] 10.1097/PAS.0000000000001544. [PMID] 32815828.
2021
Uterine PEComas: correlation between melanocytic marker expression and TSC alterations/TFE3 fusions.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. [DOI] 10.1038/s41379-021-00855-1. [PMID] 34131293.
2020
Molecular and clinicopathologic characterization of intravenous leiomyomatosis.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 33(9):1844-1860 [DOI] 10.1038/s41379-020-0546-8. [PMID] 32341498.
2020
Pediatric liver transplant following near catastrophic head bleed: Lessons learned.
Pediatric transplantation. 24(2) [DOI] 10.1111/petr.13646. [PMID] 31960553.
2018
Clinical, pathologic, cytogenetic, and molecular profiling in self-identified black women with uterine leiomyomata.
Cancer genetics. 222-223:1-8 [DOI] 10.1016/j.cancergen.2018.01.001. [PMID] 29666002.
2018
Phenotypic interpretation of complex chromosomal rearrangements informed by nucleotide-level resolution and structural organization of chromatin.
European journal of human genetics : EJHG. 26(3):374-381 [DOI] 10.1038/s41431-017-0068-0. [PMID] 29321672.
2017
Computational Prediction of Position Effects of Apparently Balanced Human Chromosomal Rearrangements.
American journal of human genetics. 101(2):206-217 [DOI] 10.1016/j.ajhg.2017.06.011. [PMID] 28735859.
2017
Implication of LRRC4C and DPP6 in neurodevelopmental disorders.
American journal of medical genetics. Part A. 173(2):395-406 [DOI] 10.1002/ajmg.a.38021. [PMID] 27759917.
2017
The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies.
Nature genetics. 49(1):36-45 [DOI] 10.1038/ng.3720. [PMID] 27841880.
2016
Fibroids: Genotype and Phenotype.
Clinical obstetrics and gynecology. 59(1):25-9 [DOI] 10.1097/GRF.0000000000000177. [PMID] 26710305.
2016
Intravenous leiomyomatosis: an unusual intermediate between benign and malignant uterine smooth muscle tumors.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 29(5):500-10 [DOI] 10.1038/modpathol.2016.36. [PMID] 26892441.
2016
Structural Chromosomal Rearrangements Require Nucleotide-Level Resolution: Lessons from Next-Generation Sequencing in Prenatal Diagnosis.
American journal of human genetics. 99(5):1015-1033 [DOI] 10.1016/j.ajhg.2016.08.022. [PMID] 27745839.
2015
Autografted Electrical Burn Complicated by Cutaneous Chromoblastomycosis.
Eplasty. 15 [PMID] 26557947.
View on: PubMed
2015
Prenatal diagnosis of chromothripsis, with nine breaks characterized by karyotyping, FISH, microarray and whole-genome sequencing.
Prenatal diagnosis. 35(3):299-301 [DOI] 10.1002/pd.4456. [PMID] 25043231.
2014
Describing sequencing results of structural chromosome rearrangements with a suggested next-generation cytogenetic nomenclature.
American journal of human genetics. 94(5):695-709 [DOI] 10.1016/j.ajhg.2014.03.020. [PMID] 24746958.
2013
Haploinsufficiency of KDM6A is associated with severe psychomotor retardation, global growth restriction, seizures and cleft palate.
Human genetics. 132(5):537-52 [DOI] 10.1007/s00439-013-1263-x. [PMID] 23354975.
2012
Clinical diagnosis by whole-genome sequencing of a prenatal sample.
The New England journal of medicine. 367(23):2226-32 [DOI] 10.1056/NEJMoa1208594. [PMID] 23215558.
2012
The selective expression of ret finger protein in endometrial cancer: can RFP be a marker of serous carcinomas?
Turk patoloji dergisi. 28(3):213-9 [DOI] 10.5146/tjpath.2012.01127. [PMID] 23011823.
2010
Disseminated peritoneal leiomyomatosis after laparoscopic supracervical hysterectomy with characteristic molecular cytogenetic findings of uterine leiomyoma.
Genes, chromosomes & cancer. 49(12):1152-60 [DOI] 10.1002/gcc.20824. [PMID] 20842731.

Education

Molecular Genetic Pathology Fellowship
2020-2021 · Brigham and Women's Hospital
Surgical Pathology Fellowship (Ob/Gyn)
2019-2020 · Massachusetts General Hospital
AP/CP Residency
2015-2019 · Massachusetts General Hosptial
Postdoctoral Research Fellowship
2011-2015 · Brigham and Women's Hospital
MD
2005-2011 · Hacettepe University Faculty of Medicine, Turkey

Contact Details

Phones:
Business:
(352) 627-9240
Emails:
Administrative Assistant:
Karen E Hyde
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