About Daniel J Perry
I am currently a Research Assistant Scientist and Co-Director of the Immune Monitoring Core at the University of Florida Diabetes Institute (UFDI). My research objectives are to elucidate the functional impact of the genetic risk variants in type 1 diabetes (T1D) pathogenesis, as well as to discover novel T1D biomarkers through a comprehensive immunophenotyping and genotyping effort.
In conjunction with complete blood counts, we developed a pipeline to efficiently process and assess over 150 immune cell subset frequencies and absolute counts per sample, which was the impetus for our Immune Monitoring Core. Our UFDI cohort has now grow to over 1000 subjects with complete comprehensive immunophenotypes, genotypes from a 975K SNP array, imputed 4-digit Class I and II HLA, as well as several other clinically relevant data. We have teamed with data scientists and biostatisticians to assist with the specialized statistical methods with the aim to link specific types of genetic risks and altered immune cell frequencies to T1D etiologies. In doing so, we are also establishing circulating immune cell reference ranges that will benefit the entire research community.
- Autoimmune Disease
- Immune Tolerance
- Immunology of Type 1 diabetes