Anthony T Yachnis, M.D.
PROF & PRDIR
About Anthony T Yachnis
Anthony T. Yachnis, M.D. is certified in anatomic pathology and neuropathology by the American Board of Pathology. As program director of the ACGME-approved neuropathology fellowship at UF, he provides a range of post-graduate neuropathology education for pathology, neurology, and neurosurgery trainees. He served on the American Board of Pathology Test Development and Advisory Committee for Neuropathology and is a past president of the American Association of Neuropathologists. Prior to his tenure at the UF College of Medicine, Dr. Yachnis completed pathology residency and a surgical pathology fellowship at the University of Pennsylvania from 1986 to 1991. He then received specialized training in pediatric neuropathology at Philadelphia Children’s Hospital in 1993.
Accomplishments
Award for Meritorious Contributions to Neuropathology
2023
·
American Association of Neuropathologists
Clinical Excellence Award
2023
·
University of Florida College of Medicine
UF College of Medicine Term Professorship
2018-2019
·
University of Florida
President, American Association of Neuropathologists
2013-2014
·
AANP
William H. Donnelly Oustanding Resident Educator Award
2012-2013
·
Department of Pathology, Immunology, and Laboratory Medicine
University of Florida College of Medicine Basic Science Teacher of the Year
2010-2011
·
University of Florida College of Medicine
Teaching Profile
Courses Taught
2019-2020,2023
BMS6020 Clinical Neuroscience
2019
GMS6705 Functional Human Neuroanatomy
2011-2014
DEN6350 General Pathology
Board Certifications
-
Anatomic and Clinical PathologyAmerican Board of Pathology
-
NeuropathologyAmerican Board of Pathology
Clinical Profile
Specialties
- Pathology, Immunology and Laboratory Medicine
Subspecialties
- Anatomic Pathology
- Neuropathology
Areas of Interest
- Adult Brain Tumors
- Epilepsy
Research Profile
Areas of Interest
- Neuropathology
- Pediatric Neuropathology
- Surgical and Eye Pathology
Open Researcher and Contributor ID (ORCID)
0000-0002-6971-0698
Publications
2024
Cerebrospinal fluid flow extends to peripheral nerves further unifying the nervous system.
Science advances.
10(36)
[DOI] 10.1126/sciadv.adn3259.
[PMID] 39231237.
2023
Cerebrospinal Fluid Flow Extends to Peripheral Nerves.
bioRxiv : the preprint server for biology.
[DOI] 10.1101/2023.11.20.567884.
[PMID] 38045235.
2022
A Pioneer of Pediatric Brain Tumors: Dr. Lucy Rorke-Adams.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.
25(1):3-5
[DOI] 10.1177/10935266211009486.
[PMID] 33872105.
2022
Central Nervous System Tumor Classification: An Update on the Integration of Tumor Genetics.
Hematology/oncology clinics of North America.
36(1):1-21
[DOI] 10.1016/j.hoc.2021.08.001.
[PMID] 34763992.
2022
Neuropathology of Alzheimer’s Disease.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics.
19(1):173-185
[DOI] 10.1007/s13311-021-01146-y.
[PMID] 34729690.
2021
Case Studies in Neuroscience: Neuropathology and diaphragm dysfunction in ventilatory failure from late-onset Pompe disease.
Journal of neurophysiology.
126(2):351-360
[DOI] 10.1152/jn.00190.2021.
[PMID] 34191636.
2021
Inflammatory myofibroblastic tumor masquerading as an anterior choroidal artery fusiform aneurysm.
Surgical neurology international.
12
[DOI] 10.25259/SNI_113_2021.
[PMID] 34221627.
2021
Orbital metastasis of squamous cell cervical cancer: A case report and review of literature.
Gynecologic oncology reports.
35
[DOI] 10.1016/j.gore.2020.100689.
[PMID] 33385055.
2021
Upfront Adjuvant Immunotherapy of Replication Repair-Deficient Pediatric Glioblastoma With Chemoradiation-Sparing Approach.
JCO precision oncology.
5:1426-1431
[DOI] 10.1200/PO.21.00153.
[PMID] 34994637.
2020
An Unusual Cause of Intracerebral Hemorrhage: Clinical Pearls Regarding Primary Angiitis of the Central Nervous System.
Neurological sciences and neurosurgery.
1(2)
[DOI] 10.47275/2692-093x-109.
[PMID] 33205146.
2020
Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases
Journal of Neuropathology and Experimental Neurology.
79(4):407-418
[DOI] 10.1093/jnen/nlaa007.
[PMID] 32106300.
2020
Novel monoclonal antibodies targeting the RRM2 domain of human TDP-43 protein.
Neuroscience letters.
738
[DOI] 10.1016/j.neulet.2020.135353.
[PMID] 32905837.
2020
Pediatric pathology all grown up – An interesting case of adult tethered spinal cord.
Surgical neurology international.
11
[DOI] 10.25259/SNI_641_2020.
[PMID] 33194295.
2020
Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier – phenotypic variability in autosomal dominant Alzheimer’s disease.
Acta neuropathologica communications.
8(1)
[DOI] 10.1186/s40478-020-0891-3.
[PMID] 32164763.
2019
Comparative analyses of the in vivo induction and transmission of -synuclein pathology in transgenic mice by MSA brain lysate and recombinant -synuclein fibrils
Acta Neuropathologica Communications.
7(1)
[DOI] 10.1186/s40478-019-0733-3.
[PMID] 31109378.
2019
Dissecting α-synuclein inclusion pathology diversity in multiple system atrophy: implications for the prion-like transmission hypothesis.
Laboratory investigation; a journal of technical methods and pathology.
99(7):982-992
[DOI] 10.1038/s41374-019-0198-9.
[PMID] 30737468.
2019
Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology.
Acta neuropathologica communications.
7(1)
[DOI] 10.1186/s40478-019-0818-z.
[PMID] 31665069.
2019
Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression.
Acta neuropathologica communications.
7(1)
[DOI] 10.1186/s40478-019-0787-2.
[PMID] 31477175.
2018
An Incidental Diffuse Midline Glioma Found at Autopsy.
Journal of forensic sciences.
63(1):316-317
[DOI] 10.1111/1556-4029.13540.
[PMID] 28508521.
2018
Deep Brain Stimulation associated gliosis: A post-mortem study.
Parkinsonism & related disorders.
54:51-55
[DOI] 10.1016/j.parkreldis.2018.04.009.
[PMID] 29653910.
2018
SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F.
The EMBO journal.
37(19)
[DOI] 10.15252/embj.201899023.
[PMID] 30206144.
2017
5 Year Expression and Neutrophil Defect Repair after Gene Therapy in Alpha-1 Antitrypsin Deficiency.
Molecular therapy : the journal of the American Society of Gene Therapy.
25(6):1387-1394
[DOI] 10.1016/j.ymthe.2017.03.029.
[PMID] 28408179.
2017
A pathologist’s perspective on induced pluripotent stem cells.
Laboratory investigation; a journal of technical methods and pathology.
97(10):1126-1132
[DOI] 10.1038/labinvest.2017.81.
[PMID] 28759008.
2017
Eleven Month Progression-Free Survival on Vemurafenib Monotherapy in a Patient With Recurrent and Metastatic BRAF V600E-Mutated Glioblastoma WHO Grade 4.
JCO precision oncology.
1:1-5
[DOI] 10.1200/PO.17.00055.
[PMID] 35172504.
2017
Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
23(2):562-574
[DOI] 10.1158/1078-0432.CCR-15-2089.
[PMID] 27521447.
2017
Pathology Residents Comprise Inspection Team for a CAP Self-Inspection.
Academic pathology.
4
[DOI] 10.1177/2374289517699230.
[PMID] 28725788.
2017
RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2.
Neuron.
95(6):1292-1305.e5
[DOI] 10.1016/j.neuron.2017.08.039.
[PMID] 28910618.
2016
Bilateral internal auditory canal gangliogliomas mimicking neurofibromatosis Type II.
Surgical neurology international.
7
[DOI] 10.4103/2152-7806.180300.
[PMID] 27127704.
2016
C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD.
Neuron.
90(3):521-34
[DOI] 10.1016/j.neuron.2016.04.005.
[PMID] 27112499.
2016
Post-mortem Findings in Huntington’s Deep Brain Stimulation: A Moving Target Due to Atrophy.
Tremor and other hyperkinetic movements (New York, N.Y.).
6
[DOI] 10.7916/D8ZP462H.
[PMID] 27127722.
2016
Second report of a Nocardia beijingensis infection in the United States: nodular scleritis with in vitro imipenem resistance.
Digital journal of ophthalmology : DJO.
22(3):62-66
[DOI] 10.5693/djo.02.2016.01.003.
[PMID] 28924404.
2015
59 Year old female with cerebellopontine angle hemorrhage.
Brain pathology (Zurich, Switzerland).
25(2):229-30
[DOI] 10.1111/bpa.12244.
[PMID] 25677066.
2015
Disseminated Intraventricular Glioneuronal Tumors: New Entity Or Variation of a Theme?
Journal of Neuropathology and Experimental Neurology.
74(6)
2015
Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits.
Acta neuropathologica communications.
3
[DOI] 10.1186/s40478-015-0252-9.
[PMID] 26566997.
2015
Optic nerve pilomyxoid astrocytoma in a patient with Noonan syndrome.
Pediatric blood & cancer.
62(6):1084-6
[DOI] 10.1002/pbc.25382.
[PMID] 25585602.
2015
RAN Translation in Huntington Disease.
Neuron.
88(4):667-77
[DOI] 10.1016/j.neuron.2015.10.038.
[PMID] 26590344.
2015
Serpin treatment suppresses inflammatory vascular lesions in temporal artery implants (TAI) from patients with giant cell arteritis.
PloS one.
10(2)
[DOI] 10.1371/journal.pone.0115482.
[PMID] 25658487.
2014
An independent elderly woman with rapid onset of coma.
JAMA neurology.
71(8):1043-7
[DOI] 10.1001/jamaneurol.2014.449.
[PMID] 24935802.
2014
CNS intraoperative consultation: a survival guide for non-neuropathologists.
Methods in molecular biology (Clifton, N.J.).
1180:369-76
[DOI] 10.1007/978-1-4939-1050-2_22.
[PMID] 25015160.
2014
Hemangioblastoma in the lung: metastatic or primary lesions?
Case reports in pathology.
2014
[DOI] 10.1155/2014/468671.
[PMID] 25574414.
2014
Inadvertent Intrathecal Vincristine Administration With Widespread Axonal Injury Demonstrated By App Immunohistochemistry
Journal of Neuropathology and Experimental Neurology.
73(6):623-624
2014
Increased precursor cell proliferation after deep brain stimulation for Parkinson’s disease: a human study.
PloS one.
9(3)
[DOI] 10.1371/journal.pone.0088770.
[PMID] 24594681.
2014
Pediatric Brainstem Tumors With Features of Angiocentric Glioma: Report of Two Cases
Journal of Neuropathology and Experimental Neurology.
73(6)
2013
Anticancer effects of niclosamide in human glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research.
19(15):4124-36
[DOI] 10.1158/1078-0432.CCR-12-2895.
[PMID] 23908450.
2013
Chondroitin sulfate proteoglycans potently inhibit invasion and serve as a central organizer of the brain tumor microenvironment.
The Journal of neuroscience : the official journal of the Society for Neuroscience.
33(39):15603-17
[DOI] 10.1523/JNEUROSCI.3004-12.2013.
[PMID] 24068827.
2013
Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression.
The Journal of clinical investigation.
123(12):5310-8
[DOI] 10.1172/JCI70314.
[PMID] 24231351.
2013
Purkinje cell loss is the major brain pathology of spinocerebellar ataxia type 10.
Journal of neurology, neurosurgery, and psychiatry.
84(12):1409-11
[DOI] 10.1136/jnnp-2013-305080.
[PMID] 23813740.
2013
Strong Zeb1 Immunoreactivity in Idh1-Positive Infiltrating Gliomas: a Possible Link Between Tumorigenic Pathways?
Journal of Neuropathology and Experimental Neurology.
72:564-565
2013
Vertebral brown tumors causing neurologic compromise.
World neurosurgery.
79(1):208.e1-6
[DOI] 10.1016/j.wneu.2010.02.022.
[PMID] 22100293.
2012
Alpha-1 Antitrypsin (Aat) Expression 1 Year After Im Administration of Raav1-Cb-Haat in a Phase 2 Clinical Trial
Molecular Therapy.
20:S91-S92
2012
Deep brain stimulation response in pathologically confirmed cases of multiple system atrophy.
Parkinsonism & related disorders.
18(1):86-8
[DOI] 10.1016/j.parkreldis.2011.09.008.
[PMID] 21983018.
2012
Gliosis versus glioma?: don’t grade until you know.
Advances in anatomic pathology.
19(4):239-49
[DOI] 10.1097/PAP.0b013e31825c6a04.
[PMID] 22692287.
2012
Meningiomas in pregnancy: a clinicopathologic study of 17 cases.
Neurosurgery.
71(5):951-61
[DOI] 10.1227/NEU.0b013e31826adf65.
[PMID] 22843130.
2012
Mutated Isocitrate Dehydrogenase-1 (Idh-1) Immunoreactive Glioblastoma With Idh-1 Negative `Pnet-Like’ Elements
Journal of Neuropathology and Experimental Neurology.
71
2012
Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains.
Brain research.
1464:61-72
[DOI] 10.1016/j.brainres.2012.04.039.
[PMID] 22652067.
2012
Neuropathologic Findings in Myotonic Dystrophy Type 2
Journal of Neuropathology and Experimental Neurology.
71:590-591
2012
Postmortem observation of collagenous lead tip region fibrosis as a rare complication of DBS.
Movement disorders : official journal of the Movement Disorder Society.
27(4):565-9
[DOI] 10.1002/mds.24916.
[PMID] 22314706.
2012
Takayasu’s arteritis: Is it a reversible disease? Case Report and Literature Review.
Surgical neurology international.
3
[DOI] 10.4103/2152-7806.102947.
[PMID] 23227437.
2011
A pilot study of human brain tissue post-magnetic resonance imaging: information from the National Deep Brain Stimulation Brain Tissue Network (DBS-BTN).
NeuroImage.
54 Suppl 1:S233-7
[DOI] 10.1016/j.neuroimage.2010.09.014.
[PMID] 20849960.
2011
Atypical Rasmussen’s encephalitis treated with temporal lobectomy.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia.
18(2):287-90
[DOI] 10.1016/j.jocn.2010.05.011.
[PMID] 21163652.
2011
Collagenous Fibrosis: a Rare Tissue Reaction of Deep Brain Stimulation (Dbs)
Journal of Neuropathology and Experimental Neurology.
70
2011
Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results.
Human gene therapy.
22(10):1239-47
[DOI] 10.1089/hum.2011.053.
[PMID] 21609134.
2011
The central nervous system solitary fibrous tumor: a review of clinical, imaging and pathologic findings among all reported cases from 1996 to 2010.
Clinical neurology and neurosurgery.
113(9):703-10
[DOI] 10.1016/j.clineuro.2011.07.024.
[PMID] 21872387.
2011
The national DBS brain tissue network pilot study: need for more tissue and more standardization.
Cell and tissue banking.
12(3):219-31
[DOI] 10.1007/s10561-010-9189-1.
[PMID] 20589432.
2011
The Neuropathology of Mucopolysaccharidosis Type Vii (Sly Disease): a Case Report and Review of the Literature
Journal of Neuropathology and Experimental Neurology.
70
2010
Atpyical Presentation and Morbidity With Rituximab in Diffuse Large B-Cell Lymphoma Infiltrating the Spine
Neuro-Oncology.
12
2010
Fragile X dementia Parkinsonism Syndrome (FXDPS).
Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology.
23(1):39-43
[DOI] 10.1097/WNN.0b013e3181b6e1b9.
[PMID] 20299862.
2010
Glioma diagnosis: immunohistochemistry and beyond.
Advances in anatomic pathology.
17(3):187-201
[DOI] 10.1097/PAP.0b013e3181d98cd9.
[PMID] 20418673.
2010
Meningiomas Resected During Pregnancy: a Clinicopathologic Study of Eight Patients
Neuro-Oncology.
12
2010
Unexpectedly Long-Term Control of Recurrent Gliomatosis Cerebri With Capecitabine: a Possible Molecular Explanation
Neuro-Oncology.
12
2009
A Posterior Fossa Embryonal Tumor in a 4-Year-Old Male With Features of Atrt But Without Ini1 Mutation
Journal of Neuropathology and Experimental Neurology.
68
2009
Hematopoietic- and neurologic-expressed sequence 1 expression in the murine GL261 and high-grade human gliomas.
Pathology oncology research : POR.
15(3):437-44
[DOI] 10.1007/s12253-008-9147-4.
[PMID] 19145478.
2009
Postmortem interval alters the water relaxation and diffusion properties of rat nervous tissue–implications for MRI studies of human autopsy samples.
NeuroImage.
44(3):820-6
[DOI] 10.1016/j.neuroimage.2008.09.054.
[PMID] 18996206.
2009
Radiographic and pathologic findings in an atypical brainstem variant of reversible posterior leukoencephalopathy syndrome.
The neurologist.
15(6):364-6
[DOI] 10.1097/NRL.0b013e3181951ac7.
[PMID] 19901722.
2008
Can standard magnetic resonance imaging reliably distinguish recurrent tumor from radiation necrosis after radiosurgery for brain metastases? A radiographic-pathological study.
Neurosurgery.
63(5):898-903; discussion 904
[DOI] 10.1227/01.NEU.0000333263.31870.31.
[PMID] 19005380.
2008
Invasion suppressor cystatin E/M (CST6): high-level cell type-specific expression in normal brain and epigenetic silencing in gliomas.
Laboratory investigation; a journal of technical methods and pathology.
88(9):910-25
[DOI] 10.1038/labinvest.2008.66.
[PMID] 18607344.
2008
Neurotropic melanoma of the trigeminal nerve: a case of atypical facial pain.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
66(3):547-50
[DOI] 10.1016/j.joms.2006.11.033.
[PMID] 18280392.
2008
Protocol for the examination of specimens from patients with tumors of the brain/spinal cord.
Archives of pathology & laboratory medicine.
132(6):907-12
[PMID] 18517271.
2008
Structure-Based Jaz Ligand-Ji and Its Analogues Show Strong Cytotoxic Effects On Glioma Cells in Vitro – a New Class of Glioma Therapy Drugs?
Journal of Neuropathology and Experimental Neurology.
67
2008
Surgical neuropathology update: a review of changes introduced by the WHO classification of tumours of the central nervous system, 4th edition.
Archives of pathology & laboratory medicine.
132(6):993-1007
[PMID] 18517285.
2008
The publishing game: reflections of an editorial team.
Laboratory investigation; a journal of technical methods and pathology.
88(12):1258-63
[DOI] 10.1038/labinvest.2008.113.
[PMID] 19020521.
2007
An orthotopic xenograft model of intraneural NF1 MPNST suggests a potential association between steroid hormones and tumor cell proliferation.
Laboratory investigation; a journal of technical methods and pathology.
87(11):1092-102
[PMID] 17876295.
2007
Diffusion tensor microscopy indicates the cytoarchitectural basis for diffusion anisotropy in the human hippocampus.
AJNR. American journal of neuroradiology.
28(5):958-64
[PMID] 17494678.
2007
Evolutionarily conserved mammalian adenine nucleotide translocase 4 is essential for spermatogenesis.
The Journal of biological chemistry.
282(40):29658-66
[PMID] 17681941.
2007
In vitro studies of steroid hormones in neurofibromatosis 1 tumors and Schwann cells.
Molecular carcinogenesis.
46(7):512-23
[PMID] 17393410.
2007
Plexiform-like neurofibromas develop in the mouse by intraneural xenograft of an NF1 tumor-derived Schwann cell line.
Journal of neuroscience research.
85(6):1347-57
[PMID] 17335073.
2007
Radiotherapy after subtotally resected or recurrent ganglioglioma.
International journal of radiation oncology, biology, physics.
67(1):244-7
[PMID] 17045420.
2006
Brainstem stereotactic biopsy sampling in children.
Journal of neurosurgery.
104(2 Suppl):108-14
[PMID] 16506498.
2006
Pontine atypical neurocytoma: case report.
Neurosurgery.
58(5)
[PMID] 16639306.
2005
Clinicopathologic and genetic profile of intracranial marginal zone lymphoma: a primary low-grade CNS lymphoma that mimics meningioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
23(24):5718-27
[PMID] 16009945.
2005
INI1 protein expression distinguishes atypical teratoid/rhabdoid tumor from choroid plexus carcinoma.
Journal of neuropathology and experimental neurology.
64(5):391-7
[PMID] 15892296.
2005
Isolated anisocoria from an endodermal cyst of the third cranial nerve mimicking an Adie’s tonic pupil.
Journal of pediatric ophthalmology and strabismus.
42(3):176-9
[PMID] 15977871.
2005
Lhermitte-Duclos disease: a report of 31 cases with immunohistochemical analysis of the PTEN/AKT/mTOR pathway.
Journal of neuropathology and experimental neurology.
64(4):341-9
[PMID] 15835270.
2005
Neonatal hypothalamic hamartoma: a differentiating nonlethal hamartoblastoma.
Journal of neurosurgery.
103(3 Suppl):277-81
[PMID] 16238084.
2005
Paraneoplastic chorea with leukoencephalopathy presenting with obsessive-compulsive and behavioral disorder.
Movement disorders : official journal of the Movement Disorder Society.
20(11):1523-7
[PMID] 16037914.
2005
Pushing the limits of radiotherapy for atypical and malignant meningioma.
American journal of clinical oncology.
28(1):70-4
[PMID] 15685038.
2004
Bone marrow transdifferentiation in brain after transplantation: a retrospective study.
Lancet (London, England).
363(9419):1432-7
[PMID] 15121406.
2004
Images of interest. Gastrointestinal: symptomatic pelvic mass.
Journal of gastroenterology and hepatology.
19(7)
[PMID] 15209632.
2004
Pituicytoma: report of two cases and clues regarding histogenesis.
Neurosurgery.
54(3):753-7; discussion 757
[PMID] 15028154.
2004
Primary adenocarcinoma of the vagina with mucinous-enteric differentiation: a report of two cases with associated vaginal adenosis without history of diethylstilbestrol exposure.
Journal of lower genital tract disease.
8(1):38-42
[PMID] 15874835.
2004
Secondary leptomeningeal sarcomatosis.
Archives of pathology & laboratory medicine.
128(11):1303-4
[PMID] 15504072.
2003
Giant cell glioblastoma and pleomorphic xanthoastrocytoma show different immunohistochemical profiles for neuronal antigens and p53 but share reactivity for class III beta-tubulin.
Archives of pathology & laboratory medicine.
127(9):1187-91
[PMID] 12946225.
2002
Cortical dysgenesis and epilepsy.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
8(4):356-71
[PMID] 12194504.
2002
Corticosteroid treatment of mitochondrial encephalomyopathies.
The neurologist.
8(5):313-5
[PMID] 12803678.
2002
Ex vivo high-resolution magnetic resonance imaging of the brain in Joubert’s syndrome.
Journal of child neurology.
17(12):911-3
[PMID] 12593466.
2002
Intraoperative consultation for nervous system lesions.
Seminars in diagnostic pathology.
19(4):192-206
[PMID] 12469787.
2002
Rhombencephalosynapsis with massive hydrocephalus: case report and pathogenetic considerations.
Acta neuropathologica.
103(3):301-4
[PMID] 11907812.
2001
Aggressive uterine sarcoma with rhabdoid features: diagnosis by peritoneal fluid cytology and absence of INI1 gene mutation.
Human pathology.
32(8):884-6
[PMID] 11521235.
2001
Tumorigenic properties of neurofibromin-deficient neurofibroma Schwann cells.
The American journal of pathology.
158(2):501-13
[PMID] 11159187.
2000
Bcl-2 immunoreactive cells with immature neuronal phenotype exist in the nonepileptic adult human brain.
Journal of neuropathology and experimental neurology.
59(2):113-9
[PMID] 10749100.
2000
CSF cytology of atypical teratoid/rhabdoid tumor of the brain in a two-year-old girl: a case report.
Diagnostic cytopathology.
23(5):329-32
[PMID] 11074628.
1999
Cerebellar and brainstem development: an overview in relation to Joubert syndrome.
Journal of child neurology.
14(9):570-3
[PMID] 10488901.
1999
Immunohistochemical localization of erythropoietin and its receptor in the developing human brain.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society.
2(2):148-58
[PMID] 9949221.
1999
Molar tooth sign in Joubert syndrome: clinical, radiologic, and pathologic significance.
Journal of child neurology.
14(6):368-76
[PMID] 10385844.
1999
Neuropathology of Joubert syndrome.
Journal of child neurology.
14(10):655-9; discussion 669
[PMID] 10511338.
1998
Characterization of a primary central nervous system atypical teratoid/rhabdoid tumor and derivative cell line: immunophenotype and neoplastic properties.
Journal of neuropathology and experimental neurology.
57(10):961-71
[PMID] 9786246.
1998
Developmental patterns of BCL-2 and BCL-X polypeptide expression in the human spinal cord.
Experimental neurology.
150(1):82-97
[PMID] 9514825.
1998
Microsporidia of the genus Trachipleistophora–causative agents of human microsporidiosis: description of Trachipleistophora anthropophthera n. sp. (Protozoa: Microsporidia).
The Journal of eukaryotic microbiology.
45(3):273-83
[PMID] 9627987.
1998
Tissue distribution of erythropoietin and erythropoietin receptor in the developing human fetus.
Early human development.
52(3):235-49
[PMID] 9808074.
1997
“Joubert syndrome” revisited: key ocular motor signs with magnetic resonance imaging correlation.
Journal of child neurology.
12(7):423-30
[PMID] 9373798.
1997
Composite pleomorphic xanthoastrocytoma and ganglioglioma: report of four cases and review of the literature.
The American journal of surgical pathology.
21(7):763-71
[PMID] 9236832.
1997
Disseminated microsporidiosis in AIDS: are any organs spared?
AIDS (London, England).
11(3):385-6
[PMID] 9147432.
1997
Distinct neurodevelopmental patterns of bcl-2 and bcl-x expression are altered in glioneuronal hamartias of the human temporal lobe.
Journal of neuropathology and experimental neurology.
56(2):186-98
[PMID] 9034373.
1997
Neuropathology of pediatric brain tumors.
Seminars in pediatric neurology.
4(4):282-91
[PMID] 9447621.
1996
Central nervous system medulloepithelioma: a series of eight cases including two arising in the pons.
Journal of neurosurgery.
84(3):430-6
[PMID] 8609554.
1996
Disseminated microsporidiosis especially infecting the brain, heart, and kidneys. Report of a newly recognized pansporoblastic species in two symptomatic AIDS patients.
American journal of clinical pathology.
106(4):535-43
[PMID] 8853044.
1996
Divergent differentiation in pleomorphic xanthoastrocytoma. Evidence for a neuronal element and possible relationship to ganglion cell tumors.
The American journal of surgical pathology.
20(1):80-5
[PMID] 8540612.
1996
Glial differentiation predicts poor clinical outcome in primitive neuroectodermal brain tumors.
Annals of neurology.
39(4):481-9
[PMID] 8619526.
1996
Rapidly progressive dementia: a clinicopathologic correlation.
Journal of geriatric psychiatry and neurology.
9(4):209-13
[PMID] 8970014.
1995
Brainstem neoplasms.
Medical and pediatric oncology.
24(6):379-87
[PMID] 7715544.
1995
Congenital CNS primitive neuroectodermal tumor: case report and review of the literature.
Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association.
15(6):949-56
[PMID] 8705205.
1995
Neurofibromatosis type 1.
Medical and pediatric oncology.
25(3):213-22
[PMID] 7623732.
1995
Neurofibromatosis type 1: pathologic substrate of high-signal-intensity foci in the brain.
Radiology.
195(3):721-4
[PMID] 7754001.
1995
Primary intracranial atypical teratoid/rhabdoid tumor in a child with Canavan disease.
Pediatric neurosurgery.
22(4):214-22
[PMID] 7619723.
1994
Acute subdural hematoma: is the blood itself toxic?
Journal of neurotrauma.
11(6):669-78
[PMID] 7723066.
1994
Cerebellar dysplasias in humans: development and possible relationship to glial and primitive neuroectodermal tumors of the cerebellar vermis.
Journal of neuropathology and experimental neurology.
53(1):61-71
[PMID] 8301321.
1994
In vivo and in vitro models of medulloblastomas and other primitive neuroectodermal brain tumors of childhood.
Molecular and chemical neuropathology.
21(2-3):219-39
[PMID] 8086035.
1994
Studies of childhood brain tumors using immunohistochemistry and microwave technology: methodological considerations.
Journal of neuroscience methods.
55(2):191-200
[PMID] 7723383.
1994
Subependymal giant cell astrocytomas in children.
Pediatric neurosurgery.
20(4):233-9
[PMID] 8043461.
1993
Expression of neuronal and glial polypeptides during histogenesis of the human cerebellar cortex including observations on the dentate nucleus.
The Journal of comparative neurology.
334(3):356-69
[PMID] 7690783.
1993
Isolated extranodal intracranial sinus histiocytosis in a 5-year-old boy. Case report.
Journal of neurosurgery.
79(5):769-73
[PMID] 8410258.
1993
The Golgi apparatus of motor neurons in amyotrophic lateral sclerosis.
Annals of neurology.
33(6):608-15
[PMID] 8498841.
1992
Desmoplastic primitive neuroectodermal tumor with divergent differentiation. Broadening the spectrum of desmoplastic infantile neuroepithelial tumors.
The American journal of surgical pathology.
16(10):998-1006
[PMID] 1384373.
1992
Expression of the neu proto-oncogene by Schwann cells during peripheral nerve development and Wallerian degeneration.
Journal of neuroscience research.
31(4):622-34
[PMID] 1374476.
1990
Isolated one-and-a-half syndrome with pontine cavernous angioma: successful surgical removal.
Journal of clinical neuro-ophthalmology.
10(4):287-90
[PMID] 2150849.
1988
Cytologic detection of amyloid in duodenal and ureteral brushings.
Diagnostic cytopathology.
4(2):133-6
[PMID] 3243158.
1988
Expression of neurofilament proteins in the hypertrophic granule cells of Lhermitte-Duclos disease: an explanation for the mass effect and the myelination of parallel fibers in the disease state.
Journal of neuropathology and experimental neurology.
47(3):206-16
[PMID] 3130464.
1984
The antagonism of bombesin in the CNS by substance P analogues.
Life sciences.
35(19):1963-9
[PMID] 6208451.
1982
Mitogenic effect of myelinated vs unmyelinated garfish nerve extracts.
Brain research.
253(1-2):349-52
[PMID] 7150974.
1982
Stimulation of DNA synthesis in Balb/c 3T3 cells by peripheral nerve degenerating in vitro.
Experimental neurology.
76(1):139-49
[PMID] 7084358.
Grants
Jun 2020
ACTIVE
1Florida Alzheimers Disease Research Center
Role: Co-Investigator
Funding: NATL INST OF HLTH NIA
May 2020
– May 2022
Analysis of Clinical and Molecular Parameters in MPNST
Role: Faculty
Funding: US ARMY MED RES ACQUISITION
Jul 2018
– Jun 2022
Genetic Studies of Neurofibromatosis
Role: Project Manager
Funding: JOHNS HOPKINS UNIVERSITY
via BLOOMBERG FAMILY FOU – PHILANTHROPIES
Jan 2018
– Feb 2020
Investigations of Neuropathologies Targeted by Clinical Trials in Alzheimers Disease Patients
Role: Principal Investigator
Funding: FL DEPT OF HLTH ED ETHEL MOORE ALZHEIMER
Aug 2015
– May 2021
University of Florida – Mt. Sinai Medical Center AD Research Center
Role: Co-Project Director/Principal Investigator
Funding: NATL INST OF HLTH NIA
Aug 2015
– Jul 2021
Efficacy of Dendritic Cell Vaccines Targeting CMV in Glioblastoma (phase 2 DC vaccine)
Role: Co-Investigator
Funding: NATL INST OF HLTH NCI
Jul 2013
– Dec 2019
Re-MATCH: Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor Adoptive Cell Therapy During Recovery from Myeloablative Chemotherapy and Hematopoietic Stem Cell Transplantation
Role: Project Manager
Funding: US ARMY MED RES ACQUISITION
Education
Fellowship
1994
·
University of Florida
Fellowship
1991
·
University of Pennsylvania
Residency
1990
·
University of Pennsylvania
M.D.
1986
·
George Washington University
Contact Details
Phones:
- Business:
- (352) 627-9252
Emails:
- Business:
- yachnis@pathology.ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100275
1600 SW ARCHER RD
GAINESVILLE FL 32610 - Business Street:
-
1600 SW ARCHER RD
GAINESVILLE FL 32610