Allison Bayer,
Associate Professor
Department:
MD-PATHOLOGY-GENERAL
Business Phone:
(352) 273-9703
Business Email:
allisonbayer@ufl.edu
Teaching Profile
Courses Taught
2024
GMS6140 Principles of Immunology
Research Profile
Open Researcher and Contributor ID (ORCID)
0000-0003-4778-0238
Publications
2023
Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T Cells
The Journal of Immunology.
211(7):1108-1122
[DOI] 10.4049/jimmunol.2200651.
[PMID] 37594278.
2023
Reversal of Experimental Autoimmune Diabetes With an sCD39/Anti-CD3 Treatment.
Diabetes.
72(11):1641-1651
[DOI] 10.2337/db23-0178.
[PMID] 37625134.
2022
CCL21 and beta-cell antigen releasing hydrogels as tolerance-inducing therapy in Type I diabetes.
Journal of controlled release : official journal of the Controlled Release Society.
348:499-517
[DOI] 10.1016/j.jconrel.2022.06.008.
[PMID] 35691500.
2021
Immunosuppressive PLGA TGF-β1 Microparticles Induce Polyclonal and Antigen-Specific Regulatory T Cells for Local Immunomodulation of Allogeneic Islet Transplants.
Frontiers in immunology.
12
[DOI] 10.3389/fimmu.2021.653088.
[PMID] 34122410.
2020
Immunomodulation Followed by Antigen-Specific Treg Infusion Controls Islet Autoimmunity
Diabetes.
69(2):215-227
[DOI] 10.2337/db19-0061.
[PMID] 31712320.
2020
In vitro platform establishes antigen-specific CD8+ T cell cytotoxicity to encapsulated cells via indirect antigen recognition.
Biomaterials.
256
[DOI] 10.1016/j.biomaterials.2020.120182.
[PMID] 32599358.
2019
CCL21 Expression in β-Cells Induces Antigen-Expressing Stromal Cell Networks in the Pancreas and Prevents Autoimmune Diabetes in Mice
Diabetes.
68(10):1990-2003
[DOI] 10.2337/db19-0239.
[PMID] 31371518.
2019
Correction to: In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD mice.
Diabetologia.
62(8)
[DOI] 10.1007/s00125-019-4922-1.
[PMID] 31190158.
2019
In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD mice.
Diabetologia.
62(7):1237-1250
[DOI] 10.1007/s00125-019-4879-0.
[PMID] 31087105.
2018
Immunoisolation of murine islet allografts in vascularized sites through conformal coating with polyethylene glycol.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
18(3):590-603
[DOI] 10.1111/ajt.14547.
[PMID] 29068143.
2017
Altered homeostasis and development of regulatory T cell subsets represent an IL-2R–dependent risk for diabetes in NOD mice
Science Signaling.
10(510)
[DOI] 10.1126/scisignal.aam9563.
[PMID] 29259102.
2017
The Folate Cycle As a Cause of Natural Killer Cell Dysfunction and Viral Etiology in Type 1 Diabetes.
Frontiers in endocrinology.
8
[DOI] 10.3389/fendo.2017.00315.
[PMID] 29218028.
2016
The Expanding Role of Natural Killer Cells in Type 1 Diabetes and Immunotherapy.
Current diabetes reports.
16(11)
[PMID] 27664042.
2015
Adoptive T Regulatory Cell Therapy for Tolerance Induction.
Current transplantation reports.
2(2):191-201
[PMID] 25938011.
2013
The IL-2/IL-2R system: from basic science to therapeutic applications to enhance immune regulation.
Immunologic research.
57(1-3):197-209
[DOI] 10.1007/s12026-013-8452-5.
[PMID] 24214027.
2012
Prevention of autoimmune diabetes and induction of β-cell proliferation in NOD mice by hyperbaric oxygen therapy.
Diabetes.
61(7):1769-78
[DOI] 10.2337/db11-0516.
[PMID] 22566533.
2011
Expansion of a restricted residual host T reg-cell repertoire is dependent on IL-2 following experimental autologous hematopoietic stem transplantation.
European journal of immunology.
41(12):3467-78
[DOI] 10.1002/eji.201141611.
[PMID] 21928285.
2011
High-resolution, noninvasive longitudinal live imaging of immune responses.
Proceedings of the National Academy of Sciences of the United States of America.
108(31):12863-8
[DOI] 10.1073/pnas.1105002108.
[PMID] 21768391.
2009
Host CD4+CD25+ T cells can expand and comprise a major component of the Treg compartment after experimental HCT.
Blood.
113(3):733-43
[DOI] 10.1182/blood-2008-08-173179.
[PMID] 18832651.
2008
A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells.
Journal of immunology (Baltimore, Md. : 1950).
181(1):225-34
[PMID] 18566388.
2008
IL-2 family of cytokines in T regulatory cell development and homeostasis.
Journal of clinical immunology.
28(6):635-9
[DOI] 10.1007/s10875-008-9235-y.
[PMID] 18726679.
2007
Function of the IL-2R for thymic and peripheral CD4+CD25+ Foxp3+ T regulatory cells.
Journal of immunology (Baltimore, Md. : 1950).
178(7):4062-71
[PMID] 17371960.
2006
Cutting edge: allogeneic CD4+CD25+Foxp3+ T regulatory cells suppress autoimmunity while establishing transplantation tolerance.
Journal of immunology (Baltimore, Md. : 1950).
176(12):7149-53
[PMID] 16751356.
2006
Quantitative assessment concerning the contribution of IL-2Rbeta for superantigen-mediated T cell responses in vivo.
International immunology.
18(4):565-72
[PMID] 16540525.
2005
Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period.
The Journal of experimental medicine.
201(5):769-77
[PMID] 15753210.
2004
Tolerance, not immunity, crucially depends on IL-2.
Nature reviews. Immunology.
4(9):665-74
[PMID] 15343366.
Grants
Sep 2024
ACTIVE
Restoration of immune regulation in type 1 diabetes through the synergistic action of insulin-like growth factor-1 and interleukin-2
Role: Co-Project Director/Principal Investigator
Funding: BREAKTHROUGH T1D – formerly JDRF Intl
Jun 2024
ACTIVE
Combination therapy with Ladarixin and anti-CD3 for the prevention of Type 1 diabetes in NOD mice
Role: Principal Investigator
Funding: DOMPE PHARMACEUTICALS
Mar 2024
ACTIVE
Conformal islet encapsulation for transplantation at vascularized sites to allow physiological insulin secretion
Role: Principal Investigator
Funding: UNIV OF MIAMI
via NATL INST OF HLTH
Sep 2023
ACTIVE
Role of mTORC1 signaling in type 1 diabetes
Role: Principal Investigator
Funding: UNIV OF MIAMI
via NATL INST OF HLTH
Sep 2023
ACTIVE
GLUT1 Inhibition in type 1 diabetes
Role: Principal Investigator
Funding: CITY OF HOPE
via BREAKTHROUGH T1D – formerly JDRF Intl
Sep 2023
– Sep 2024
Combinational immune therapies with antigen-specific Tregs for tolerance induction in islet transplantation
Role: Principal Investigator
Funding: BREAKTHROUGH T1D – formerly JDRF Intl
Sep 2023
– Aug 2024
Use of dimethyl fumarate for targeting autoimmunity in type 1 diabetes
Role: Principal Investigator
Funding: UNIV OF MIAMI
via NATL INST OF HLTH NIAID
Sep 2020
ACTIVE
Engineering Immunomodulatory Nanoscale Coatings for Protecting Islet Transplants
Role: Co-Project Director/Principal Investigator
Funding: NATL INST OF HLTH NIDDK
Contact Details
Phones:
- Business:
- (352) 273-9703
Emails:
- Business:
- allisonbayer@ufl.edu
Addresses:
- Business Mailing:
-
PO Box 100275
GAINESVILLE FL 32610 - Business Street:
-
BMS J581
1275 Center Drive
GAINESVILLE FL 32610