Allison Bayer

Allison Bayer,

Associate Professor

Department: MD-PATHOLOGY-GENERAL
Business Phone: (352) 273-9703
Business Email: allisonbayer@ufl.edu

Teaching Profile

Courses Taught
2024
GMS6140 Principles of Immunology

Research Profile

Open Researcher and Contributor ID (ORCID)

0000-0003-4778-0238

Publications

2023
Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T Cells
The Journal of Immunology. 211(7):1108-1122 [DOI] 10.4049/jimmunol.2200651. [PMID] 37594278.
2023
Reversal of Experimental Autoimmune Diabetes With an sCD39/Anti-CD3 Treatment.
Diabetes. 72(11):1641-1651 [DOI] 10.2337/db23-0178. [PMID] 37625134.
2022
CCL21 and beta-cell antigen releasing hydrogels as tolerance-inducing therapy in Type I diabetes.
Journal of controlled release : official journal of the Controlled Release Society. 348:499-517 [DOI] 10.1016/j.jconrel.2022.06.008. [PMID] 35691500.
2021
Immunosuppressive PLGA TGF-β1 Microparticles Induce Polyclonal and Antigen-Specific Regulatory T Cells for Local Immunomodulation of Allogeneic Islet Transplants.
Frontiers in immunology. 12 [DOI] 10.3389/fimmu.2021.653088. [PMID] 34122410.
2020
Immunomodulation Followed by Antigen-Specific Treg Infusion Controls Islet Autoimmunity
Diabetes. 69(2):215-227 [DOI] 10.2337/db19-0061. [PMID] 31712320.
2020
In vitro platform establishes antigen-specific CD8+ T cell cytotoxicity to encapsulated cells via indirect antigen recognition.
Biomaterials. 256 [DOI] 10.1016/j.biomaterials.2020.120182. [PMID] 32599358.
2019
CCL21 Expression in β-Cells Induces Antigen-Expressing Stromal Cell Networks in the Pancreas and Prevents Autoimmune Diabetes in Mice
Diabetes. 68(10):1990-2003 [DOI] 10.2337/db19-0239. [PMID] 31371518.
2019
Correction to: In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD mice.
Diabetologia. 62(8) [DOI] 10.1007/s00125-019-4922-1. [PMID] 31190158.
2019
In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD mice.
Diabetologia. 62(7):1237-1250 [DOI] 10.1007/s00125-019-4879-0. [PMID] 31087105.
2018
Immunoisolation of murine islet allografts in vascularized sites through conformal coating with polyethylene glycol.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 18(3):590-603 [DOI] 10.1111/ajt.14547. [PMID] 29068143.
2017
Altered homeostasis and development of regulatory T cell subsets represent an IL-2R–dependent risk for diabetes in NOD mice
Science Signaling. 10(510) [DOI] 10.1126/scisignal.aam9563. [PMID] 29259102.
2017
The Folate Cycle As a Cause of Natural Killer Cell Dysfunction and Viral Etiology in Type 1 Diabetes.
Frontiers in endocrinology. 8 [DOI] 10.3389/fendo.2017.00315. [PMID] 29218028.
2016
The Expanding Role of Natural Killer Cells in Type 1 Diabetes and Immunotherapy.
Current diabetes reports. 16(11) [PMID] 27664042.
2015
Adoptive T Regulatory Cell Therapy for Tolerance Induction.
Current transplantation reports. 2(2):191-201 [PMID] 25938011.
2013
The IL-2/IL-2R system: from basic science to therapeutic applications to enhance immune regulation.
Immunologic research. 57(1-3):197-209 [DOI] 10.1007/s12026-013-8452-5. [PMID] 24214027.
2012
Prevention of autoimmune diabetes and induction of β-cell proliferation in NOD mice by hyperbaric oxygen therapy.
Diabetes. 61(7):1769-78 [DOI] 10.2337/db11-0516. [PMID] 22566533.
2011
Expansion of a restricted residual host T reg-cell repertoire is dependent on IL-2 following experimental autologous hematopoietic stem transplantation.
European journal of immunology. 41(12):3467-78 [DOI] 10.1002/eji.201141611. [PMID] 21928285.
2011
High-resolution, noninvasive longitudinal live imaging of immune responses.
Proceedings of the National Academy of Sciences of the United States of America. 108(31):12863-8 [DOI] 10.1073/pnas.1105002108. [PMID] 21768391.
2009
Host CD4+CD25+ T cells can expand and comprise a major component of the Treg compartment after experimental HCT.
Blood. 113(3):733-43 [DOI] 10.1182/blood-2008-08-173179. [PMID] 18832651.
2008
A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells.
Journal of immunology (Baltimore, Md. : 1950). 181(1):225-34 [PMID] 18566388.
2008
IL-2 family of cytokines in T regulatory cell development and homeostasis.
Journal of clinical immunology. 28(6):635-9 [DOI] 10.1007/s10875-008-9235-y. [PMID] 18726679.
2007
Function of the IL-2R for thymic and peripheral CD4+CD25+ Foxp3+ T regulatory cells.
Journal of immunology (Baltimore, Md. : 1950). 178(7):4062-71 [PMID] 17371960.
2006
Cutting edge: allogeneic CD4+CD25+Foxp3+ T regulatory cells suppress autoimmunity while establishing transplantation tolerance.
Journal of immunology (Baltimore, Md. : 1950). 176(12):7149-53 [PMID] 16751356.
2006
Quantitative assessment concerning the contribution of IL-2Rbeta for superantigen-mediated T cell responses in vivo.
International immunology. 18(4):565-72 [PMID] 16540525.
2005
Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period.
The Journal of experimental medicine. 201(5):769-77 [PMID] 15753210.
2004
Tolerance, not immunity, crucially depends on IL-2.
Nature reviews. Immunology. 4(9):665-74 [PMID] 15343366.

Grants

Sep 2023 ACTIVE
Combinational immune therapies with antigen-specific Tregs for tolerance induction in islet transplantation
Role: Principal Investigator
Funding: JDRF
Sep 2020 ACTIVE
Engineering Immunomodulatory Nanoscale Coatings for Protecting Islet Transplants
Role: Co-Project Director/Principal Investigator
Funding: NATL INST OF HLTH NIDDK

Contact Details

Phones:
Business:
(352) 273-9703
Emails:
Addresses:
Business Mailing:
PO Box 100275
GAINESVILLE FL 32610
Business Street:
BMS J581
1275 Center Drive
GAINESVILLE FL 32610