Maigan A Brusko

Maigan A Brusko,

RES AST SCTST

Department: MD-PATHOLOGY-GENERAL
Business Phone: (352) 273-9300
Business Email: maigan@ufl.edu

Publications

2021
A Novel Single Cell RNA-seq Analysis of Non-Myeloid Circulating Cells in Late Sepsis.
Frontiers in immunology. 12 [DOI] 10.3389/fimmu.2021.696536. [PMID] 34484194.
2021
Single-Cell RNA-seq of Human Myeloid-Derived Suppressor Cells in Late Sepsis Reveals Multiple Subsets With Unique Transcriptional Responses: A Pilot Study.
Shock (Augusta, Ga.). 55(5):587-595 [DOI] 10.1097/SHK.0000000000001671. [PMID] 33021571.
2020
Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood.
Frontiers in immunology. 11 [DOI] 10.3389/fimmu.2020.00611. [PMID] 32351504.
2020
Identification of Unique mRNA and miRNA Expression Patterns in Bone Marrow Hematopoietic Stem and Progenitor Cells After Trauma in Older Adults.
Frontiers in immunology. 11 [DOI] 10.3389/fimmu.2020.01289. [PMID] 32670283.
2020
Immunomodulatory Dual-Sized Microparticle System Conditions Human Antigen Presenting Cells Into a Tolerogenic Phenotype In Vitro and Inhibits Type 1 Diabetes-Specific Autoreactive T Cell Responses.
Frontiers in immunology. 11 [DOI] 10.3389/fimmu.2020.574447. [PMID] 33193362.
2020
Innate inflammation drives NK cell activation to impair Treg activity.
Journal of autoimmunity. 108 [DOI] 10.1016/j.jaut.2020.102417. [PMID] 32035746.
2019
Dendritic Cells Treated with Exogenous Indoleamine 2,3-Dioxygenase Maintain an Immature Phenotype and Suppress Antigen-specific T cell Proliferation.
Journal of immunology and regenerative medicine. 5 [DOI] 10.1016/j.regen.2019.100015. [PMID] 31788580.
2017
An antigen-specific semi-therapeutic treatment with local delivery of tolerogenic factors through a dual-sized microparticle system blocks experimental autoimmune encephalomyelitis.
Biomaterials. 143:79-92 [DOI] 10.1016/j.biomaterials.2017.07.029. [PMID] 28772190.
2016
Antithymocyte Globulin Plus G-CSF Combination Therapy Leads to Sustained Immunomodulatory and Metabolic Effects in a Subset of Responders With Established Type 1 Diabetes.
Diabetes. 65(12):3765-3775 [PMID] 27669730.
View on: PubMed
2015
Anti-Thymocyte Globulin/G-Csf Treatment Preserves Beta Cell Function in Patients With Established Type 1 Diabetes
The Journal of clinical investigation. 125(1):448-455 [DOI] 10.1172/JCI78492. [PMID] 25500887.
2013
Autologous umbilical cord blood infusion followed by oral docosahexaenoic acid and vitamin D supplementation for C-peptide preservation in children with Type 1 diabetes.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 19(7):1126-9 [DOI] 10.1016/j.bbmt.2013.04.011. [PMID] 23611977.
2013
Human Treg Responses Allow Sustained Recombinant Adeno-Associated Virus-Mediated Transgene Expression
The Journal of clinical investigation. 123(12):5310-5318 [DOI] 10.1172/JCI70314. [PMID] 24231351.
2013
The autoimmune disease-associated SNP rs917997 of IL18RAP controls IFN╬│ production by PBMC.
Journal of autoimmunity. 44:8-12 [DOI] 10.1016/j.jaut.2013.06.001. [PMID] 23891168.
2012
Central role for interleukin-2 in type 1 diabetes.
Diabetes. 61(1):14-22 [DOI] 10.2337/db11-1213. [PMID] 22187370.
2011
Autologous umbilical cord blood transfusion in young children with type 1 diabetes fails to preserve C-peptide.
Diabetes care. 34(12):2567-9 [DOI] 10.2337/dc11-1406. [PMID] 22011412.
2011
Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients With Type 1 Diabetes
Journal of Immunology. 186(7):3918-3926 [DOI] 10.4049/jimmunol.1003099. [PMID] 21368230.
2009
Influence of membrane CD25 stability on T lymphocyte activity: implications for immunoregulation.
PloS one. 4(11) [DOI] 10.1371/journal.pone.0007980. [PMID] 19956753.

Grants

Aug 2021 ACTIVE
Human Pancreas Analysis Program (HPAP)
Role: Co-Investigator
Funding: UNIV OF PENNSYLVANIA via NATL INST OF HLTH NIDDK
May 2021 ACTIVE
Dysfunctional Myelopoiesis and Myeloid-Derived Suppressor Cells in Sepsis Pathobiology
Role: Co-Investigator
Funding: NATL INST OF HLTH NIGMS
Feb 2020 ACTIVE
Human Atlas of Neonatal Developmental and Early Life Pancreas / Immunity (HANDEL)-P/I Continuation
Role: Co-Investigator
Funding: HELMSLEY CHARITABLE TRUST, LEONA & HARRY

Contact Details

Phones:
Business:
(352) 273-9300
Emails:
Business:
maigan@ufl.edu