Carla N Mavian

Carla N Mavian,

Assistant Scientist

Department: MD-PATHOLOGY-GENERAL
Business Phone: (352) 265-7796
Business Email: cmavian@ufl.edu

About Carla N Mavian

I obtained my bachelor and master in biotechnology from University of Padova, Italy. I obtained my PhD in the Centro de Biología Molecular Severo Ochoa hosted at the Autonomous University of Madrid, Spain, mentored by Dr. Antonio Alcami. My PhD focused on evolution and immunodynamics of poxviruses. I joined the University of Florida during my postdoctoral training mentored by Dr. Maureen Goodenow and Dr. Marco Salemi.

Accomplishments

Mentor
2020 · University Multicultural Mentor Program
Co-organizer
2019-Current · International Bioinformatics Workshop on Virus Evolution and Molecular Epidemiology
Software & Data Carpentry Certified Instructor
2019-Current · Data Carpentry
Board Member
2019 · UF Carpentries Club
Instructor
2018-Current · International Bioinformatics Workshop on Virus Evolution and Molecular Epidemiology
Thomas H. Maren Awardee
2017-2019 · UF College of Medicine
Young Investigator Award
2017 · American Society of Tropical Medicine and Hygiene
Young Investigator Award
2015 · Conference of Retrovirology and Opportunistic Infections

Research Profile

My research program supports cross-disciplinary approaches to the study of infectious diseases. My area of research is infectious diseases, with emphasis on molecular evolution and host-pathogen interactions. My research spans from large-scale epidemic processes, such as population growth and spatial epidemic dispersal, to small-scale transmission histories; and within-host evolution, including adaptation and recombination. My Google Scholar profile: https://scholar.google.com/citations?user=1nPwPo4AAAAJ&hl=en&oi=ao

Open Researcher and Contributor ID (ORCID)

0000-0003-3819-5520

Publications

2021
Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis and poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets.
Journal of neurovirology. 27(1):101-115 [DOI] 10.1007/s13365-020-00927-z. [PMID] 33405206.
2021
Comparative Pathogenesis, Genomics and Phylogeography of Mousepox
Viruses. 13(6) [DOI] 10.3390/v13061146. [PMID] 34203773.
2021
Emergence of porcine delta-coronavirus pathogenic infections among children in Haiti through independent zoonoses and convergent evolution.
medRxiv : the preprint server for health sciences. [DOI] 10.1101/2021.03.19.21253391. [PMID] 33791709.
2021
Rapid emergence and spread of SARS-CoV-2 gamma (P.1) variant in Haiti.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. [DOI] 10.1093/cid/ciab736. [PMID] 34471930.
2021
Sociodemographic, Ecological, and Spatiotemporal Factors Associated with Human Immunodeficiency Virus Drug Resistance in Florida: A Retrospective Analysis.
The Journal of infectious diseases. 223(5):866-875 [DOI] 10.1093/infdis/jiaa413. [PMID] 32644119.
2021
Trophic transfer and toxicity of heavy metals from dengue mosquito Aedes aegypti to predator dragonfly Tramea cophysa.
Ecotoxicology (London, England). 30(6):1108-1115 [DOI] 10.1007/s10646-021-02448-9. [PMID] 34165678.
2020
A minor population of macrophage-tropic HIV-1 variants is identified in recrudescing viremia following analytic treatment interruption.
Proceedings of the National Academy of Sciences of the United States of America. 117(18):9981-9990 [DOI] 10.1073/pnas.1917034117. [PMID] 32300019.
2020
A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis.
JMIR public health and surveillance. 6(2) [DOI] 10.2196/19170. [PMID] 32412415.
2020
Authors’ Reply to: Errors in Tracing Coronavirus SARS-CoV-2 Transmission Using a Maximum Likelihood Tree. Comment on “A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis”.
JMIR public health and surveillance. 6(4) [DOI] 10.2196/24661. [PMID] 33174844.
2020
Collection of SARS-CoV-2 Virus from the Air of a Clinic Within a University Student Health Care Center and Analyses of the Viral Genomic Sequence.
Aerosol and air quality research. 20(6):1167-1171 [DOI] 10.4209/aaqr.2020.02.0202. [PMID] 33424954.
2020
Correction: A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis.
JMIR public health and surveillance. 6(3) [DOI] 10.2196/22853. [PMID] 32776889.
2020
Differing impacts of global and regional responses on SARS-CoV-2 transmission cluster dynamics.
bioRxiv : the preprint server for biology. [DOI] 10.1101/2020.11.06.370999. [PMID] 33173870.
2020
Employing Molecular Phylodynamic Methods to Identify and Forecast HIV Transmission Clusters in Public Health Settings: A Qualitative Study.
Viruses. 12(9) [DOI] 10.3390/v12090921. [PMID] 32842636.
2020
Multiple Recombination Events and Strong Purifying Selection at the Origin of SARS-CoV-2 Spike Glycoprotein Increased Correlated Dynamic Movements.
International journal of molecular sciences. 22(1) [DOI] 10.3390/ijms22010080. [PMID] 33374797.
2020
Sampling bias and incorrect rooting make phylogenetic network tracing of SARS-COV-2 infections unreliable.
Proceedings of the National Academy of Sciences of the United States of America. 117(23):12522-12523 [DOI] 10.1073/pnas.2007295117. [PMID] 32381734.
2020
Toxigenic Vibrio cholerae evolution and establishment of reservoirs in aquatic ecosystems.
Proceedings of the National Academy of Sciences of the United States of America. 117(14):7897-7904 [DOI] 10.1073/pnas.1918763117. [PMID] 32229557.
2020
Under-the-Radar Dengue Virus Infections in Natural Populations of Aedes aegypti Mosquitoes.
mSphere. 5(2) [DOI] 10.1128/mSphere.00316-20. [PMID] 32350095.
2019
Emergence of Madariaga virus as a cause of acute febrile illness in children, Haiti, 2015-2016.
PLoS neglected tropical diseases. 13(1) [DOI] 10.1371/journal.pntd.0006972. [PMID] 30629592.
2019
Isolation of Mayaro Virus from a Venezuelan Patient with Febrile Illness, Arthralgias, and Rash: Further Evidence of Regional Strain Circulation and Possible Long-Term Endemicity.
The American journal of tropical medicine and hygiene. 101(6):1219-1225 [DOI] 10.4269/ajtmh.19-0357. [PMID] 31595869.
2019
Mayaro as a Caribbean traveler: Evidence for multiple introductions and transmission of the virus into Haiti.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 87:151-153 [DOI] 10.1016/j.ijid.2019.07.031. [PMID] 31382049.
2018
A new “American” subgroup of African-lineage Chikungunya virus detected in and isolated from mosquitoes collected in Haiti, 2016.
PloS one. 13(5) [DOI] 10.1371/journal.pone.0196857. [PMID] 29746539.
2018
Detection and phylogenetic characterization of arbovirus dual-infections among persons during a chikungunya fever outbreak, Haiti 2014.
PLoS neglected tropical diseases. 12(5) [DOI] 10.1371/journal.pntd.0006505. [PMID] 29851952.
2018
Distribution and characterization of Shiga toxin converting temperate phages carried by Shigella flexneri in Hispaniola.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 65:321-328 [DOI] 10.1016/j.meegid.2018.07.038. [PMID] 30075254.
2018
Islands as Hotspots for Emerging Mosquito-Borne Viruses: A One-Health Perspective.
Viruses. 11(1) [DOI] 10.3390/v11010011. [PMID] 30585228.
2018
Madariaga Virus: Identification of a Lineage III Strain in a Venezuelan Child With Acute Undifferentiated Febrile Illness, in the Setting of a Possible Equine Epizootic.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 67(4):619-621 [DOI] 10.1093/cid/ciy224. [PMID] 29718127.
2017
Emergence of recombinant Mayaro virus strains from the Amazon basin.
Scientific reports. 7(1) [DOI] 10.1038/s41598-017-07152-5. [PMID] 28821712.
2017
Fatal Systemic Salmonellosis in a Florida Manatee ( Trichechus manatus latirostris).
Journal of wildlife diseases. 53(4):930-933 [DOI] 10.7589/2017-01-012. [PMID] 28463629.
2017
Phylodynamic applications in 21st century global infectious disease research.
Global health research and policy. 2 [DOI] 10.1186/s41256-017-0034-y. [PMID] 29202081.
2017
Ranavirus phylogenomics: Signatures of recombination and inversions among bullfrog ranaculture isolates.
Virology. 511:330-343 [DOI] 10.1016/j.virol.2017.07.028. [PMID] 28803676.
2016
Concurrence of Iridovirus, Polyomavirus, and a Unique Member of a New Group of Fish Papillomaviruses in Lymphocystis Disease-Affected Gilthead Sea Bream
Journal Of Virology. 90(19):8768-8779 [DOI] 10.1128/JVI.01369-16.
2014
Genome Sequence of WAU86/88-1, a New Variant of Vaccinia Virus Lister Strain from Poland.
Genome announcements. 2(1) [DOI] 10.1128/genomeA.01086-13. [PMID] 24407630.
2014
The genome sequence of ectromelia virus Naval and Cornell isolates from outbreaks in North America.
Virology. 462-463:218-26 [DOI] 10.1016/j.virol.2014.06.010. [PMID] 24999046.
2012
Complete genome sequence of the European sheatfish virus.
Journal of virology. 86(11):6365-6 [DOI] 10.1128/JVI.00618-12. [PMID] 22570241.
2012
The genome sequence of the emerging common midwife toad virus identifies an evolutionary intermediate within ranaviruses.
Journal of virology. 86(7):3617-25 [DOI] 10.1128/JVI.07108-11. [PMID] 22301140.
2009
Presentation of cytosolically stable peptides by HLA-B27 is not dependent on the canonic interactions of N-terminal basic residues in the A pocket.
Journal of immunology (Baltimore, Md. : 1950). 182(1):446-55 [PMID] 19109176.
View on: PubMed
A snapshot of SARS-CoV-2 genome availability up to 30th March, 2020 and its implications
. [DOI] 10.1101/2020.04.01.020594.
A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis (Preprint)
. [DOI] 10.2196/preprints.19170.
Authors’ Reply to: Errors in Tracing Coronavirus SARS-CoV-2 Transmission Using a Maximum Likelihood Tree. Comment on “A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis” (Preprint)
. [DOI] 10.2196/preprints.24661.
Brain tissue transcriptomic analysis of SIV-infected macaques identifies Poly (ADP-ribose) polymerases (PARPs) as potential biomarkers for neuropathogenesis.
. [DOI] 10.21203/rs.3.rs-30629/v1.
Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis, and Poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets
. [DOI] 10.1101/2020.05.21.109140.
Correction: A Snapshot of SARS-CoV-2 Genome Availability up to April 2020 and its Implications: Data Analysis (Preprint)
. [DOI] 10.2196/preprints.22853.
Recombination and purifying selection preserves covariant movements of mosaic SARS-CoV-2 protein S
. [DOI] 10.1101/2020.03.30.015685.

Grants

May 2020 ACTIVE
Forecasting trajectories of HIV transmission networks with a novel phylodynamic and deep learning framework
Role: Co-Investigator
Funding: NATL INST OF HLTH NIAID
Apr 2020 ACTIVE
RAPID: Dynamic Identification of SARS-COV-2 Transmission Epicenters in Presence of Spatial Heterogeneity (COV-DYNAMITE)
Role: Co-Investigator
Funding: NATL SCIENCE FOU
Apr 2017 – Mar 2019
Salivary microRNA as novel biomarkers of HIV/AIDS disease progression in people living with HIV.
Role: Principal Investigator
Funding: UF FOU

Education

Postdoctoral Research
2014-2018 · University of Florida
PhD
2013 · Universidad Autonoma de Madrid

Contact Details

Phones:
Business:
(352) 265-7796
Emails:
Business:
cmavian@ufl.edu